Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J M Whalley"'
Publikováno v:
Equine Veterinary Journal. 36:341-345
Summary Reasons for performing study: A silent cycle of equine herpesvirus 1 infection has been described following epidemiological studies in unvaccinated mares and foals. In 1997, an inactivated whole virus EHV-1 and EHV-4 vaccine was released comm
Autor:
K. Hansen, M. T. Koen, L. Seshadri, D. Birch, E. Bell, J. M. Whalley, H. W. Stokes, S. Bradford, I. Napier, Martin Messerle
Publikováno v:
Archives of Virology. 151:2389-2405
The 150-kbp genome of the alphaherpesvirus equine herpesvirus 1 (EHV-1) strain HVS25A was cloned as a bacterial artificial chromosome (EHV-1 BAC), with mini F plasmid sequences inserted between genes 62 and 63. Transfection of EHV-1 BAC DNA purified
Publikováno v:
Veterinary Microbiology. 88:13-25
Equine herpesvirus 1 (EHV-1) is a major cause of respiratory disease and abortion in horses worldwide. Although some vaccines have been shown experimentally to reduce disease, there are few reports of the responses to vaccination in the field. This s
Publikováno v:
Archives of Virology. 145:2677-2686
The equine herpesvirus 1 (EHV-1) strain HVS25A regulatory genes IE and UL5, encoding homologues of herpes simplex virus 1 (HSV-1) ICP4 and ICP27 respectively, were cloned into a eukaryotic expression vector and the DNA injected intramuscularly into m
Publikováno v:
Archives of Virology. 145:2371-2385
Insertional mutagenesis was used to construct an equine herpesvirus 1 (EHV-1) mutant in which the open reading frame for glycoprotein D was replaced by a lacZ cassette. This gD deletion mutant (delta gD EHV-1) was unable to infect normally permissive
Publikováno v:
Veterinary Microbiology. 68:27-34
The prevalence of EHV-1 and EHV-4 antibody-positive horses was determined using a type specific ELISA on serum samples collected from 229 mares and their foals resident on a large Thoroughbred stud farm in the Hunter Valley of New South Wales in Febr
Publikováno v:
Veterinary Microbiology. 68:35-48
The potential of DNA-mediated immunisation to protect against equine herpesvirus 1 (EHV-1) disease was assessed in a murine model of EHV-1 respiratory infection. Intramuscular injection with DNA encoding the EHV-1 envelope glycoprotein D (gD) in a ma
Publikováno v:
Veterinary Microbiology. 60:1-11
Equine herpesvirus-1 (EHV-1) glycoproteins H, and L (gH and gL) expressed individually or co-expressed by recombinant baculoviruses were used to immunise BALB/c mice prior to intranasal challenge in a murine model of respiratory infection. Only the c
Publikováno v:
Archives of Virology. 141:1785-1793
Equine herpesvirus 1 glycoprotein D (EHV-1 gD) expressed constitutively in mammalian cell lines had similar electrophoretic mobility to gD produced in EHV-1 infected cells but lacked a possibly complexed higher molecular weight form seen in the latte