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Akademický článek

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Origin, proliferation and differentiation of Leydig cells

Autor: R Habert, Hervé Lejeune, J. M. Saez

Publikováno v: Journal of Molecular Endocrinology
Journal of Molecular Endocrinology, BioScientifica, 1998, 20, pp.1-25

Mammalian sex determination involves complex interacting networks of cellular and hormonal signals leading to the development of male or female phenotypes. Three main sequential processes are involved: first, the establishment of chromosomal sex at f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499b68ef3d8a9abbfc9f549319e6318f
https://doi.org/10.1677/jme.0.0200001

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Expression and regulation of Gαq and Gαll mRNAs and proteins in bovine adrenal cells

Autor: Dominique Langlois, A. Derrien, J. M. Saez

Publikováno v: Molecular and Cellular Endocrinology. 121:65-74

Bovine adrenal cortical cells (BAC) express corticotropin (ACTH) and angiotensin II (AngII) receptors (AT1 subtype), which are coupled to adenylate cyclase and phosphoinositide pathways, respectively. The coupling of AT1 to phosphoinositide breakdown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37b5fc742fee7dfa5ff1ebab7931d8d7
https://doi.org/10.1016/0303-7207(96)03852-x

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Effects of transforming growth factor-beta 1 on human adrenocortical fasciculata-reticularis cell differentiated functions

Autor: Danielle Naville, Martine Begeot, J. M. Saez, Marie-Christine Lebrethon, C. Jaillard

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 79:1033-1039

Transforming growth factor-beta 1 (TGF beta 1) has been reported to have a strong inhibitory effect on the specific function of adrenal cells of several species. In the present study, we examined the effects of TGF beta 1 on cultured human fasciculat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a84d37848f84d68350bbb831b2785d
https://doi.org/10.1210/jcem.79.4.7962271

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Stimulatory effect of follicle-stimulating hormone on basal and luteinizing hormone-stimulated testosterone secretions by the fetal rat testis in vitro

Autor: Christine Levacher, René Habert, C. Gautier, Virginie Rouiller-Fabre, L Lecerf, J M Saez

Publikováno v: Endocrinology. 133:2313-2318

The in vitro effect of FSH on testosterone secretion by the fetal rat testis was studied. Testes were cultured in the presence or absence of either commercial human (h) FSH (Metrodine; 200 mIU/ml) or recombinant hFSH (200 mIU/ml) for 3 days and with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d0ea4b62121e36649bd1750da51b5d
https://doi.org/10.1210/endo.133.5.8404683

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Akademický článek

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Nuclear receptors Nor1 and NGFI-B/Nur77 play similar, albeit distinct, roles in the hypothalamo-pituitary-adrenal axis

Autor: P M, Fernandez, F, Brunel, M A, Jimenez, J M, Saez, S, Cereghini, M M, Zakin

Publikováno v: Endocrinology. 141(7)

Studies in Nur77-deficient mice have shown that the basal regulation of hypothalamic and pituitary functions as well as the adrenocortical steroidogenesis in these animals is normal. This indicates that Nur77-related orphan receptors may substitute N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aaeb6401cdb5bd2cb21f775728c80d52
https://pubmed.ncbi.nlm.nih.gov/10875239

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Transcriptional and translational regulation of angiotensin II type 2 receptor by angiotensin II and growth factors

Autor: J Y, Li, O, Avallet, M C, Berthelon, D, Langlois, J M, Saez

Publikováno v: Endocrinology. 140(11)

The regulatory effects of angiotensin-II (AngII) and several growth factors, including insulin-like growth factor 1 (IGF-1), basic fibroblast growth factor (bFGF), and transforming growth factor beta1 (TGFbeta1) on the AngII subtype 2 (AT2) receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e357a40e779b691a7c01c7ca3bd20cbd
https://pubmed.ncbi.nlm.nih.gov/10537123

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Characterization of the muscarinic receptor subtype M3 in the bovine zona fasciculata-reticularis cells by receptor binding, mRNA and functional studies

Autor: J M Saez, A Janossy, J. Y. Li

Publikováno v: Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 1999, 136, pp.329-336

In the present work we have investigated which muscarinic (M) receptor subtype is responsible for the steroidogenic effect of muscarinic agonists in bovine zona fasciculata-reticularis (ZFR) cells in culture. Radioligand binding studies using the mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a6621b81f19fb49c26d8c7a1a028fb
https://hal.inrae.fr/hal-02688214

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