Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J M Moerschbaecher"'
Publikováno v:
CNS Drug Reviews. 5:43-58
Autor:
C P, France, S C, Ahn, L L, Brockunier, J R, Bagley, M R, Brandt, P J, Winsauer, J M, Moerschbaecher
Publikováno v:
Pharmacology Biochemistry and Behavior. 59:295-303
Several fentanyl derivatives have been reported to have novel pharmacologies that might be exploited for developing alternate approaches to the treatment of pain. The purpose of the current series of studies was to evaluate OHM3507, a novel fentanyl
Publikováno v:
Psychopharmacology. 123:9-14
The effects of scopolamine were evaluated in monkeys responding under operant procedures designed to evaluate drug effects on learning and memory. In one procedure, responding was maintained by food presentation under a multiple schedule. One compone
Publikováno v:
Pharmacology, biochemistry, and behavior. 64(2)
Three monkeys discriminated 1.78 mg/kg of mirfentanil while responding under a fixed-ratio 5 schedule of stimulus-shock termination. Two mirfentanil derivatives, OHM3295 and OHM10579, substituted for mirfentanil in all subjects. However, other drugs
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
As a means of characterizing the role of 5-hydroxytryptamine (5-HT1A) receptors in learning, a full 5-HT1A receptor agonist, 8-hydroxy-dipropylaminotetralin (8-OH-DPAT), was administered both alone and in combination with two partial agonists (buspir
Autor:
J, Brodkin, J M, Moerschbaecher
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(3)
The effects of cannabinoid ligands were studied in rats responding under a repeated acquisition procedure. Each session rats were required to learn a different three-response sequence; every third correct completion of the sequence resulted in the pr
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(1)
A multiple schedule of repeated acquisition and performance of conditional discriminations was used to characterize the effects of two negative allosteric modulators of the gamma-aminobutyric acid (GABAA) receptor (ethyl beta-carboline-3-carboxylate
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 20(5)
1. It has been reported that subconvulsive doses of convulsant agents such as strychnine and pentylenetetrazole can enhance memory in rodents studied under various behavioral procedures. The present study was designed to determine if similar results
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
Responding by squirrel monkeys was maintained by food presentation under a repeated acquisition of behavioral chains procedure. Monkeys acquired a different three-response chain each session. Sequence completions were reinforced under a fixed-ratio 5
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 257(2)
MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine maleate] and related compounds were studied in monkeys discriminating between 0.032 mg/kg of (+)-MK-801 and saline and in a separate group of monkeys responding under a multipl