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Discovery of Alpha-1-Proteinase Inhibitor Binding Peptides from the Screening of a Solid Phase Combinatorial Peptide Library

Autor: D. H. Hammond, P. D. Bastek, George A. Baumbach, Ruben G. Carbonell, J. M. Land

Publikováno v: Separation Science and Technology. 35:1681-1706

Alpha-1-proteinase inhibitor (A1PI, also known as alpha-1-antitrypsin), a blood plasma protein, was radiolabeled and screened against a portion of a hexameric, solid-phase combinatorial peptide library. The screening of 2% of a library containing 34

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::015bbfeb3c232dadc3e11db12317e192
https://doi.org/10.1081/ss-100102488

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The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease

Autor: M. S. Tanner, J. M. Land, James R. Bonham, M. Downing, A. Fensom, C. Rittey, P. Guthrie, D. O'Neill, Mark Sharrard, Lynette D. Fairbanks, J. C. Allen, John A. Duley

Publikováno v: Journal of Inherited Metabolic Disease. 22:174-184

Thirty-three children ranging from 2 weeks to 12 years of age were selected for allopurinol loading, 16 on the basis of an increased urinary ourotate excretion detected by routine organic acid analysis (group A), and 17 for clinical reasons suggestin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b8bb194684547fec8af9b7da6274d8
https://doi.org/10.1023/a:1005406205548

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Some observations on a comparative aerial photography interpretation of a landslipped area

Autor: J. M. Land, S. G. Dale, P. G. Fookes

Publikováno v: Quarterly Journal of Engineering Geology. 24:249-265

All aerial photography interpretation must be used with caution. When well done and supported by ground truth exercises they can be a valuable aid to site investigation, depending on the quality and scale of the aerial photographs and the skill and b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd83bb91a69051b70cef953e33853678
https://doi.org/10.1144/gsl.qjeg.1991.024.03.01

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Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

Autor: C S, Casley, L, Canevari, J M, Land, J B, Clark, M A, Sharpe

Publikováno v: Journal of neurochemistry. 80(1)

Disrupted energy metabolism, in particular reduced activity of cytochrome oxidase (EC 1.9.3.1), alpha-ketoglutarate dehydrogenase (EC 1.2.4.2) and pyruvate dehydrogenase (EC 1.2.4.1) have been reported in post-mortem Alzheimer's disease brain. beta-A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f69ebf3fb8d75a83e0be0b703b804e6
https://pubmed.ncbi.nlm.nih.gov/11796747

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