Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators

Autor: Johann Foloppe, Charlotte Quentin-Froignant, Sokunthea Top, J. M. Lagarde, Nathalie Silvestre, Philippe Erbs, Renée Brandely, Doris Schmitt, Stéphane Bertagnoli, Annie Findeli, Franck Gallardo, Sandrine Kappler-Gratias, Kerstin Bystricky, Renaud Morin, Catherine Brua

Publikováno v: Biomedicines
Biomedicines, MDPI, 2020, 8 (12), pp.543. ⟨10.3390/biomedicines8120543⟩
Biomedicines, Vol 8, Iss 543, p 543 (2020)
Volume 8
Issue 12

International audience; As a live biologic agent, oncolytic vaccinia virus has the ability to target and selectively amplify at tumor sites. We have previously reported that deletion of thymidine kinase and ribonucleotide reductase genes in vaccinia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4ea01b130bf684add3de2a3da993f7
https://hal.inrae.fr/hal-03196860/file/biomedicines-08-00543-v2.pdf

Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma

Autor: Renaud Morin, Don-Marc Franchini, Loic Ysebaert, Christine Bezombes, Cédric Rossi, J. M. Lagarde, Jean-Jacques Fournié, Christine Jean, Ariel Savina, Julie Bordenave, Mary Poupot, Patricia Pérez-Galán, Alba Matas Céspedes, Camille Laurent, Pauline Gravelle, Marie Tosolini, Emilie Decaup, Christian Klein, Laetitia Ligat

Publikováno v: OncoImmunology
OncoImmunology, 2018, 8 (3), pp.1554175. ⟨10.1080/2162402X.2018.1554175⟩
OncoImmunology, Taylor & Francis, 2018, 8 (3), pp.1554175. ⟨10.1080/2162402X.2018.1554175⟩
OncoImmunology, Vol 8, Iss 3 (2019)

International audience; Follicular lymphoma (FL) is a common non Hodgkin's lymphoma subtype in which immune escape mechanisms are implicated in resistance to chemo-immunotherapy. Although molecular studies point to qualitative and quantitative deregu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35785d231a0f4f836a157ff339b0514e
https://www.hal.inserm.fr/inserm-02472186

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Evaluation by quantitative image analysis of anticancer drug activity on multicellular spheroids grown in 3D matrices

Autor: Elise Demange, Zied Souguir, Adrien Russo, Guillaume Vidal, Valérie Lobjois, Aurélie Gomes, Pauline Pannetier, Bernard Ducommun, J. M. Lagarde

Publikováno v: Oncology Letters

Pharmacological evaluation of anticancer drugs using 3D in vitro models provides invaluable information for predicting in vivo activity. Artificial matrices are currently available that scale up and increase the power of such 3D models. The aim of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de317be5e10271bfc94f8d0211679bac
https://pubmed.ncbi.nlm.nih.gov/28105152

A new stochastic inverse identification of the mechanical properties of human skin

Autor: Jean-Michel Bergheau, J. M. Lagarde, Gwendal Josse, Alexandre Delalleau, Rosario Toscano, Hassan Zahouani

Publikováno v: Engineering Optimization. 43:61-75

The study of the mechanical properties of human skin is a key point to better understand surgery, skin ageing and pathologies. As the skin is a living tissue, it must be studied in vivo, hence analytical solutions are really difficult to obtain. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::382d4aa57959b4aab741242e2cdc12be
https://doi.org/10.1080/03052151003739606