Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J M Frazier"'
Publikováno v:
Toxicological Sciences. 72:19-30
The relationship between cytotoxicity and kinetics of cadmium uptake was investigated in primary rat hepatocyte cultures. Primary rat hepatocytes were exposed to cadmium concentrations ranging from 1.0 to 80 micro M in albumin-free buffer or 32 to 8,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdfde1caf2a3c28bac4bd25d1fb8f56
https://doi.org/10.1093/toxsci/kfg009
https://doi.org/10.1093/toxsci/kfg009
Autor:
J. M. Frazier, N. J. Delraso
Publikováno v:
Toxicology Methods. 9:97-114
Primary rat hepatocytes area useful research tool for direct investigation of hepatotoxic effects of chemicals or drugs at the cellular level. USEPA's reevaluation of current human health risk assessment models for thetoxicmetal cadmium has identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc502cee0ecc6ed095944ee98044fe1
https://doi.org/10.1080/105172399242753
https://doi.org/10.1080/105172399242753
Autor:
K. T. Geiss, J. M. Frazier
The potential toxicities of compounds to replace current US Air Force operational chemicals is of particular interest. A group of jet fuel system ice-inhibiting agent alternatives currently being evaluated for performance include derivations of 1 ,3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950a6baaf270e53bca8635e81a95a4e0
https://doi.org/10.21236/ada453166
https://doi.org/10.21236/ada453166
Autor:
C Toxopeus, J M Frazier
The isolated perfused rat liver system (IPRL) is a useful tool in studying the role of the liver in the kinetics and metabolism 0 chemicals. A better understanding of how chemicals are taken up, metabolized and excreted by the liver will help to pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ad842b68a7c116d677e30994db6ef1
https://doi.org/10.21236/ada453185
https://doi.org/10.21236/ada453185
Autor:
J M Frazier, W S Din
Publikováno v:
Biochemical Journal. 230:395-402
An isolated rat hepatocyte preparation was used to study the cellular toxicity of cadmium and the protective effects of metallothionein on cadmium-induced toxicity. Exposure of primary suspension cultures of isolated rat hepatocytes to Cd2+ (0-35.7 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74966dc112fe21e882f9d6bfe5a95b8d
https://doi.org/10.1042/bj2300395
https://doi.org/10.1042/bj2300395
Publikováno v:
Veterinary Pathology. 24:515-524
Excessive copper storage in livers of feral white perch ( Morone americana) from the Chesapeake Bay is described. Age-related, progressive accumulation of hepatic copper in levels often exceeding 1,000 μg/g wet weight was associated with peribiliary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205fc264477386a7e04792a7878a4f47
https://doi.org/10.1177/030098588702400608
https://doi.org/10.1177/030098588702400608
Publikováno v:
Marine Biology. 76:63-66
Oysters, Ostrea edulis, were exposed to cadmium (0.1 mg l-1) for up to 110 d (in 1982) under laboratory conditions in order to determine the effect of Cd exposure on blood amoebocytes. The results demonstrate that Cd-accumulation does not alter the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7bfd309d682135911e0205d6b76acf1
https://doi.org/10.1007/bf00393056
https://doi.org/10.1007/bf00393056
Autor:
B. S. Kingsley, J. M. Frazier
Publikováno v:
American Journal of Physiology-Cell Physiology. 236:C139-C143
The hypothesis that one component of cadmium uptake by rat hepatocytes involves a mediated transport pathway normally operative for zinc transport was tested in the isolated perfused rat liver preparation. Excess zinc in the perfusion medium suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c517575c4773e9cc4392a08a87efac8
https://doi.org/10.1152/ajpcell.1979.236.3.c139
https://doi.org/10.1152/ajpcell.1979.236.3.c139
Autor:
S.G. George, J. M. Frazier
Publikováno v:
Marine Biology. 76:55-61
The accumulation of cadmium was investigated in two species of oysters [Crassostrea gigas (L.) and Ostrea edulis (L.)] from the same environment and in oysters of the same species (O. edulis) from two different environments (contaminated and uncontam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be41b2a1f3c922bca7c32be9163a7a9b
https://doi.org/10.1007/bf00393055
https://doi.org/10.1007/bf00393055
Publikováno v:
Journal of Applied Physiology. 31:154-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3643b7cdf5117fe7060126c58f0fe778
https://doi.org/10.1152/jappl.1971.31.1.154
https://doi.org/10.1152/jappl.1971.31.1.154