Zobrazeno 1 - 10
of 105
pro vyhledávání: '"J M Dietschy"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 8, Pp 1598-1611 (1997)
These studies were done to determine whether an underlying metabolic difference could account for the higher concentration of cholesterol carried in low density lipoproteins (LDL-C) in male hyperresponder (HR) cynomolgus monkeys than in their hypores
Externí odkaz:
https://doaj.org/article/c582d3f1d7aa4629afa2c282881f105d
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 9, Pp 1953-1961 (1996)
Several lines of evidence have suggested that central nervous system development and function depend upon a supply of cholesterol that comes from low density lipoproteins (LDL-C). These studies test this hypothesis directly by measuring in vivo the u
Externí odkaz:
https://doaj.org/article/a585bdc8178c476294fd4ba57a36f478
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 1, Pp 67-79 (1995)
The suitability of the adult male cynomolgus monkey as a model for investigating genetic mechanisms that regulate dietary cholesterolemic response was evaluated by carrying out a systematic characterization of the major aspects of cholesterol metabol
Externí odkaz:
https://doaj.org/article/38416e8952314626a020a7b7a8904b4d
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 9, Pp 1661-1673 (1994)
The concentration of cholesterol carried in low density lipoproteins (LDL-C) is primarily determined by the rate at which LDL-C is produced (Jt) and the rate at which the liver takes up this particle through receptor-dependent transport (Jm). The acc
Externí odkaz:
https://doaj.org/article/8c289c939d704fb585ed1044947e28e5
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 2, Pp 328-339 (1994)
These experiments systematically evaluated the dual-isotope plasma ratio method for measuring intestinal cholesterol absorption in the hamster. It was found that while the ratio of the 3H- and 14C-labeled cholesterol in the plasma, relative to the re
Externí odkaz:
https://doaj.org/article/193346d9b85a4a1cbca2f4ad48115b00
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 4, Pp 551-569 (1981)
This study was undertaken to determine the rates of sterol synthesis and uptake in the major organs of the female rat in vivo. At the mid-dark phase of the light cycle, control animals, animals in which hepatic sterol synthesis had been selectively i
Externí odkaz:
https://doaj.org/article/18e0fcbfa64241cfa93bf9782dd45b28
Autor:
E F Stange, J M Dietschy
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 1, Pp 72-82 (1983)
In an effort to localize small intestinal sterol synthesis both along the length of the intestine and along the villus-crypt axis, we defined the optimal conditions to measure absolute rates of digitonin-precipitable sterol (DPS) synthesis in whole i
Externí odkaz:
https://doaj.org/article/31f29cecaf00405b8246a55d97f02122
Autor:
D K Spady, J M Dietschy
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 3, Pp 303-315 (1983)
This study was undertaken to measure and compare the rates at which digitonin-precipitable sterols (DPS) were synthesized in vivo in the major organs of five different animal species. These rates were assessed by measuring the velocity at which [3H]w
Externí odkaz:
https://doaj.org/article/cf90c6265b144115b48f35cdfd68ed2b
Autor:
D J Jeske, J M Dietschy
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 3, Pp 364-376 (1980)
This study was undertaken to determine the mechanisms that regulate cholesterol synthesis in vivo and to quantitate the relative importance of the liver and extrahepatic tissues as sites for sterol synthesis. Rats were administered [3H]water intraven
Externí odkaz:
https://doaj.org/article/f5da60d0a2ed487abae791d0779ed248
Autor:
S D Turley, J M Dietschy
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 8, Pp 923-934 (1979)
These studies were designed to determine the importance of the rate of hepatic cholesterol synthesis, the size of the hepatic cholesteryl ester pool, the amount of chylomicron cholesterol reaching the liver, and the rate of bile acid transport into b
Externí odkaz:
https://doaj.org/article/c555e9191e1a4647ac95441af2193706