Zobrazeno 1 - 10
of 76
pro vyhledávání: '"J M Capasso"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 267:H2050-H2057
The purpose of this study was to characterize the effect of chronic treatment with an angiotensin-converting enzyme (ACE) inhibitor on left ventricular function in spontaneously hypertensive rats (SHR). Cilazapril (5 mg/kg) was administered in the dr
Publikováno v:
Journal of Cardiovascular Pharmacology. 23:584-593
Summary: To determine whether cardiac unloading by inhibition of angiotensin I (AI) to AII conversion by captopril or blockade of the AII receptor (AT1) by losartan was more effective in prevention of the detrimental hemodynamic consequences of myoca
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H1953-H1964
Mechanical performance and cytosolic Ca2+ dynamics were characterized in myocytes isolated from left and right ventricles of rats with ischemic heart failure. Seven days after coronary artery narrowing (CAN) in rats filling pressures were elevated, w
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H713-H724
In an attempt to elucidate the effects of two major risk factors of heart failure in humans, high blood pressure and coronary artery disease, renal hypertension and coronary artery constriction were induced singularly and in combination in rats, and
Autor:
Piero Anversa, C. J. Homcy, J. M. Capasso, Peng Li, Harer Huang, Leonard G. Meggs, J. Coupet, Wei Cheng
Publikováno v:
Circulation Research. 72:1149-1162
To determine the effects of acute myocardial infarction on the regulation of angiotensin II (Ang II) receptors and contractile performance of left and right ventricular myocytes, coronary artery ligation was surgically induced in rats, and Ang II rec
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H2056-H2067
To determine the effects of coronary arterial occlusion on the contractile response of the heart to angiotensin II (ANG II) administration, large infarcts were surgically induced in Sprague-Dawley rats at 2 mo of age. Forty-eight hours later, hearts
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1411-H1421
A procedure for calculating left ventricular wall stresses segmentally was devised. Rectangular coordinates of the wall surfaces as seen in longitudinal section were plotted with the long axis as the x-axis. For each cavity point, a third-order polyn
Autor:
J. M. Capasso, Piero Anversa, G. Bianchi, Antonio Schiavone, E. English, P. Benatti, R. Micheletti, E. D. Di Paola
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H1111-H1117
To determine whether propionyl-L-carnitine (PLC) administration ameliorates ventricular remodeling after myocardial infarction, we performed coronary occlusion in rats and examined the long-term effects of the drug 19-24 wk after surgery. In view of
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 264:H760-H769
To determine the relationship between reactive cardiac hypertrophy and the expression of angiotensin II (ANG II) receptors in surviving myocytes after infarction, large infarcts were produced in rats that were killed 2–3 days later. Measurements of
Publikováno v:
Cardiovascular Research. 27:145-157