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Akademický článek
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Autor:
T, Müller, B, Robaye, R P, Vieira, D, Ferrari, M, Grimm, T, Jakob, S F, Martin, F, Di Virgilio, J-M, Boeynaems, J C, Virchow, M, Idzko
Publikováno v:
Allergy. 65(12)
Extracellular ATP contributes to the pathogenesis of asthma via signalling at purinergic receptors. However, the precise purinergic receptors subtypes mediating the pro-asthmatic effects of ATP have not been identified, yet.In vivo studies were perfo
Autor:
J M, Boeynaems
Publikováno v:
Revue medicale de Bruxelles. 30(4)
Following the important growth of the Belgian laboratory medicine budget in the eighties, the mechanisms of reimbursement by the social security system have become more and more complex in the last 20 years. The current system is a dual one, with a l
Publikováno v:
The Journal of physiology. 564(Pt 1)
Extracellular nucleotides are important regulators of epithelial ion transport, frequently exerting their action from the luminal side. Luminal P2Y receptors have previously been identified in rat distal colonic mucosa. Their activation by UTP and AT
Autor:
J M, Boeynaems, B, Gulbis, F, Cotton, J, Decuyper, F X, Demoor, C, Gervy, P, Macours, P, Thiry
Publikováno v:
Revue medicale de Bruxelles. 23
The laboratory of clinical chemistry performs more than 300 different tests in biochemistry, hormone and tumor markers analysis, therapeutic drug monitoring and toxicology. For the most basic tests it has followed the trend of clinical chemistry towa
Publikováno v:
The Journal of biological chemistry. 276(19)
The P2Y(11) receptor is an ATP receptor positively coupled to the cAMP and phosphoinositide pathways. Ssf1 is a Saccharomyces cerevisiae nuclear protein, which plays an important role in mating. The gene encoding the human orthologue of SSF1 is adjac
Publikováno v:
Cellular signalling. 12(6)
Nucleotides are ubiquitous intercellular messengers whose actions are mediated by specific receptors. Since the first clonings in 1993, it is known that nucleotide receptors belong to two families: the ionotropic P2X receptors and the metabotropic P2
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 45(7)
It is well known that ICAM-1 expression can be stimulated by TNF and by oxidative stress, via the activation of specific transcription factors. Two of these--NFkappaB and AP-1--can also be activated by reactive oxygen species, including the superoxid
Publikováno v:
Journal of cellular physiology. 175(3)
Alpha-MSH, a proopiomelanocortin (POMC)-derived peptide, is known to be produced in the pituitary, the skin, and melanoma tumors and to possess many biological effects, mainly on melanocyte pigmentation and growth. Moreover, the melanocyte expresses
Publikováno v:
Revue medicale de Bruxelles. 17(4)
Cardiovascular diseases are a frequent cause of morbidity and mortality in our country. The early detection of risk factors by laboratory tests and the subsequent preventive treatment may have a substantial beneficial effect on public health. However