Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J M, Williamson"'
Autor:
Sally J. M. Williamson, Ewan E. Morrison, John Thompson, Michael E. Cheetham, Philip A. Robinson
Publikováno v:
Journal of Neurochemistry. 116:342-349
Parkin is an ubiquitin-protein ligase mutated in Autosomal Recessive - Juvenile Parkinsonism. Here, we describe a cell-based assay to measure Parkin's ubiquitin-protein ligase activity. It relies on the ability of Parkin to recognise depolarised mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aad3a80ae9f386cbdd2e0051fafa5e1
https://doi.org/10.1111/j.1471-4159.2010.07113.x
https://doi.org/10.1111/j.1471-4159.2010.07113.x
Autor:
Francis L, Martin, Sally J M, Williamson, Katerina E, Paleologou, David, Allsop, Omar M A, El-Agnaf
Publikováno v:
Protein and peptide letters. 11(3)
Lesions known as Lewy bodies (LBs) and Lewy neurites (LNs) characterise brains of Parkinson's disease (PD) patients. Intracellular aggregation of alpha-synuclein (alpha-syn) appears to play a key role in the generation of LBs and LNs. Such aggregatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cce831fbd49810d5d9ddb24a528f6dc1
https://pubmed.ncbi.nlm.nih.gov/15182224
https://pubmed.ncbi.nlm.nih.gov/15182224
Autor:
Francis L, Martin, Sally J M, Williamson, Katerina E, Paleologou, Rebecca, Hewitt, Omar M A, El-Agnaf, David, Allsop
Publikováno v:
Journal of neurochemistry. 87(3)
Lewy bodies in the brains of patients with Parkinson's disease (PD) contain aggregates of alpha-synuclein (alpha-syn). Missense mutations (A53T or A30P) in the gene encoding alpha-syn are responsible for rare, inherited forms of PD. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e09196d846fbb4aa4088303df0e8fa0a
https://pubmed.ncbi.nlm.nih.gov/14535945
https://pubmed.ncbi.nlm.nih.gov/14535945
Publikováno v:
Statistics in medicine. 18(11)
Generalized estimating equations (GEE) methodology as proposed by Liang and Zeger has received widespread use in the analysis of correlated binary data. Miller et al. and Lipsitz et al. extended GEE to correlated nominal and ordinal categorical data;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1a6ed1ad92182a3dd5dd808574cc9a8
https://pubmed.ncbi.nlm.nih.gov/10399205
https://pubmed.ncbi.nlm.nih.gov/10399205
Autor:
H X, Barnhart, J M, Williamson
Publikováno v:
Biometrics. 54(2)
Analysis of data with repeated measures is often accomplished through the use of generalized estimating equations (GEE) methodology. Although methods exist for assessing the adequacy of the fitted models for uncorrelated data with likelihood methods,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c261cfaab0766f5548b8fd58f43b7c8
https://pubmed.ncbi.nlm.nih.gov/9629652
https://pubmed.ncbi.nlm.nih.gov/9629652
Autor:
J M, Williamson, A K, Manatunga
Publikováno v:
Biometrics. 53(2)
Estimation of interrater agreement for ordered categorical data is examined when the same sample is being assessed by various raters with different methods. We investigate the use of a latent model proposed by Qu, Piedmonte, and Medendorp (1995, Biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9546ef9fedec5c0cc98dbc9bb7bae275
https://pubmed.ncbi.nlm.nih.gov/9192459
https://pubmed.ncbi.nlm.nih.gov/9192459
Publikováno v:
Blood. 85(9)
The Wiskott-Aldrich syndrome (WAS) is an X-linked (Xp11.22) recessive immunodeficiency syndrome characterized by susceptibility to opportunistic and pyogenic infections, thrombocytopenia, and eczema. Previous studies of obligate carriers of WAS docum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6853e9d77f24cf3344e99e13ef16f31e
https://pubmed.ncbi.nlm.nih.gov/7537115
https://pubmed.ncbi.nlm.nih.gov/7537115
Autor:
Steven Adams, E. A. Bogdanov, Vladimir Demidov, Anatoly Kudryavtsev, J. M. Williamson, Mark Koepke
Publikováno v:
Physics of Plasmas. 19:023510
Temporal measurements of the emission intensities of the Ar 419.8 and 420.1 nm spectral lines combined with Ar plasma modeling were used to examine the metastable atom and electron density behavior in the initial stage of a pulsed dc discharge. The e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f722b1806b5059ac0595ab9b71cee75
https://doi.org/10.1063/1.3686142
https://doi.org/10.1063/1.3686142
Publikováno v:
Physics of Plasmas. 17:103502
Two–dimensional (2D) simulations of a dc glow discharge with a cold cathode in argon have been performed for various radii of the discharge tube. It is shown that the loss of the charged particles to the walls can significantly affect plasma parame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a51cf83f6e011918e426d6398bb336d
https://doi.org/10.1063/1.3486525
https://doi.org/10.1063/1.3486525
Publikováno v:
Physics of Plasmas. 16:104501
It is experimentally demonstrated that energetic electrons originating from the cathode or produced in volumetric processes in the cathode region of a cold cathode direct current discharge can create a large potential drop in the near-wall sheath. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67d1a01888666a93287c78d832e90432
https://doi.org/10.1063/1.3257914
https://doi.org/10.1063/1.3257914