Zobrazeno 1 - 10 of 19 pro vyhledávání: '"J M, WOODCOCK"'
1
In vitro activity of BAY 12-8039, a new fluoroquinolone
Autor: F J Boswell, Richard J. S. Wise, N P Brenwald, J M Woodcock, J. M. Andrews
Publikováno v: Antimicrobial Agents and Chemotherapy. 41:101-106
The in vitro activity of BAY 12-8039, a new fluoroquinolone, was studied in comparison with those of ciprofloxacin, trovafloxacin (CP 99,219), cefpodoxime, and amoxicillin-clavulanate against gram-negative, gram-positive, and anaerobic bacteria. Its
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae2f80d3f95f60d7703a2134c9e2fcf
https://doi.org/10.1128/aac.41.1.101
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2
The in-vitro activity of faropenem, a novel oral penem
Autor: J M Woodcock, J. P. Ashby, Richard J. S. Wise, J. M. Andrews, N. Brenwald
Publikováno v: Journal of Antimicrobial Chemotherapy. 39:35-43
The in-vitro activity of faropenem, a novel oral penem, was studied in comparison with other beta-lactam antimicrobials against 711 recent clinical isolates including Gram-negative, Gram-positive and anaerobic bacteria. MIC data showed that faropenem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ab85c6cca891a71921b720f3351cf4
https://doi.org/10.1093/jac/39.1.35
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3
Concentration of amoxycillin and clavulanate in lung compartments in adults without pulmonary infection
Autor: J. M. Andrews, J M Woodcock, Richard J. S. Wise, P J Cook, David Honeybourne
Publikováno v: Thorax. 49:1134-1138
BACKGROUND--The efficacy of an antibiotic is usually predicted from serum levels and MIC90 values for likely pathogens, but in the lung tissue concentrations may be more informative. This study compares concentrations of amoxycillin and clavulanate i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d32aee570e989f930dc5fc40a124b0e
https://doi.org/10.1136/thx.49.11.1134
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5
Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival
Autor: M A, Guthridge, F C, Stomski, E F, Barry, W, Winnall, J M, Woodcock, B J, McClure, M, Dottore, M C, Berndt, A F, Lopez
Publikováno v: Molecular cell. 6(1)
In the hemopoietic compartment, IL-3, GM-CSF, and IL-5 receptors are major transducers of survival signals; however, the receptor-proximal events that determine this vital function have not been defined. We have found that IL-3 stimulation induces ph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b5ede987afd0be61fdc0416ab647ccd2
https://pubmed.ncbi.nlm.nih.gov/10949031
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6
Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine binding site of their receptors
Autor: Q, Sun, K, Jones, B, McClure, B, Cambareri, B, Zacharakis, P O, Iversen, F, Stomski, J M, Woodcock, C J, Bagley, R, D'Andrea, A F, Lopez
Publikováno v: Blood. 94(6)
Human interleukin-5 (IL-5), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-3 are eosinophilopoietic cytokines implicated in allergy in general and in the inflammation of the airways specifically as seen in asthma. All 3 cytokines f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eec5935c9ab0c1b2d24eae9b3a2cd877
https://pubmed.ncbi.nlm.nih.gov/10477723
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7
Receptors of the cytokine superfamily: mechanisms of activation and involvement in disease
Autor: J M, Woodcock, C J, Bagley, A F, Lopez
Publikováno v: Bailliere's clinical haematology. 10(3)
Cytokine receptors are members of a diverse family of proteins that serve the dual function of recognizing their cognate ligands among a plethora of other factors and of initiating a series of cellular signals that ultimately lead to multiple cellula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57e34131f5427b42ffe74bda8528ea40
https://pubmed.ncbi.nlm.nih.gov/9421613
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8
The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5
Autor: J M, Woodcock, B J, McClure, F C, Stomski, M J, Elliott, C J, Bagley, A F, Lopez
Publikováno v: Blood. 90(8)
The granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor is expressed on normal and malignant hematopoietic cells as well as on cells from other organs in which it transduces a variety of functions. Despite the widespread expression and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b42d6c5b58005f26c834fcbec29b4c05
https://pubmed.ncbi.nlm.nih.gov/9376581
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10
The comparative pharmacokinetics and tissue penetration of single-dose ciprofloxacin 400 mg i.v. and 750 mg po
Autor: J M Woodcock, Richard J. S. Wise, J. M. Andrews, C R Catchpole
Publikováno v: The Journal of antimicrobial chemotherapy. 33(1)
The pharmacokinetics of ciprofloxacin following single doses of 400 mg i.v. and 750 mg po were compared in six healthy volunteers. Concentrations of ciprofloxacin were measured in plasma, cantharides induced blister fluid and urine, by microbiologica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86df9f62201b02524cc7b9cf79a0729
https://pubmed.ncbi.nlm.nih.gov/8157550
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