Zobrazeno 1 - 10 of 47 pro vyhledávání: '"J M, Strong"'
1
Field-Scale Migration of Colloidal Tracers in a Fractured Shale Saprolite
Autor: William E. Sanford, J. M. Strong, Larry D. McKay
Publikováno v: Ground Water. 38:139-147
A field-scale tracer experiment carried out under natural gradient ground water flow conditions showed that colloids can be highly mobile in a fractured and highly weathered shale saprolite. Four colloidal tracers (0.100 {mu}m fluorescent latex micro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03235097c2693432f14ff073640b8cd9
https://doi.org/10.1111/j.1745-6584.2000.tb00211.x
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2
Determination of cerebral glucose transport and metabolic kinetics by dynamic MR spectroscopy
Autor: Chrit T. W. Moonen, P. C. M. Van Zijl, Scott M. Eleff, D. Davis, J. M. Strong, R. J. Parker
Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 273:E1216-E1227
A new in vivo nuclear magnetic resonance (NMR) spectroscopy method is introduced that dynamically measures cerebral utilization of magnetically labeled [1-13C]glucose from the change in total brain glucose signals on infusion. Kinetic equations are d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c8ec9580914203421bff504aa2a969
https://doi.org/10.1152/ajpendo.1997.273.6.e1216
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3
Pressure-Sensitive Paint Measurements on a Supersonic High-Sweep Oblique Wing Model
Autor: J. A. Schreiner, J. M. Strong, B. G. McLachlan, Robert A. Kennelly, James H. Bell, Martin Gouterman, H. Park, Jean Gallery, Stephen C. Smith
Publikováno v: Journal of Aircraft. 32:217-227
The pressure-sensitive paint method was used in the test of a high-sweep oblique wing model, conducted in the NASA Ames 9- by 7-ft Supersonic Wind Tunnel. Surface pressure data was acquired from both the luminescent paint and conventional pressure ta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1aedbfa19cd2e9d2bcc84dfa68b98482
https://doi.org/10.2514/3.56921
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6
Effects of cytochrome P450 inducers on 17alpha-ethinyloestradiol (EE2) conjugation by primary human hepatocytes
Autor: A P, Li, N R, Hartman, C, Lu, J M, Collins, J M, Strong
Publikováno v: British journal of clinical pharmacology. 48(5)
Our objective was to elucidate further the underlying mechanism responsible for therapeutic failures observed with concomitant administration of the oral contraceptive 17alpha-ethinyloestradiol (EE2 ) and rifampicin.We investigated both oxidative and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a7b9e794376e6a3d301efd92cec8250
https://pubmed.ncbi.nlm.nih.gov/10594476
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7
Potentially reactive cyclic carbamate metabolite of the antiepileptic drug felbamate produced by human liver tissue in vitro
Autor: I M, Kapetanovic, C D, Torchin, C D, Thompson, T A, Miller, P J, McNeilly, T L, Macdonald, H J, Kupferberg, J L, Perhach, R D, Sofia, J M, Strong
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 26(11)
Felbamate (FBM) is a novel antiepileptic drug that was approved in 1993 for treatment of several forms of epilepsy. After its introduction, toxic reactions (aplastic anemia and hepatotoxicity) associated with its use were reported. It is unknown whet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74b4692c4ae8d27670a2cff6093082a1
https://pubmed.ncbi.nlm.nih.gov/9806951
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8
The in vitro metabolism of penclomedine in mouse, rat, and human systems
Autor: N R, Hartman, K U, Leo, T G, Brewer, J M, Strong
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 26(6)
Penclomedine is a multi-chlorinated alpha-picoline derivative that has demonstrated activity in several murine breast cancer models and is currently in clinical testing for use against solid tumors. This study evaluates the metabolism of penclomedine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b22d460c8448624e3b6738ce64750841
https://pubmed.ncbi.nlm.nih.gov/9616185
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9
The involvement of cytochrome P450 3A4 in the N-demethylation of L-alpha-acetylmethadol (LAAM), norLAAM, and methadone
Autor: D E, Moody, M E, Alburges, R J, Parker, J M, Collins, J M, Strong
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 25(12)
The N-demethylation of LAAM, norLAAM, and methadone has been investigated in human liver microsomes and microsomes containing cDNA-expressed human P450s. Gas chromatography/mass spectrometry methods allowed detection of norLAAM and dinorLAAM formatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f21e9ddef8c4bda61cfe8e01de327f1c
https://pubmed.ncbi.nlm.nih.gov/9394023
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10
Effect of albumin on the estimation, in vitro, of phenytoin Vmax and Km values: implications for clinical correlation
Autor: L K, Ludden, T M, Ludden, J M, Collins, H S, Pentikis, J M, Strong
Publikováno v: The Journal of pharmacology and experimental therapeutics. 282(1)
The effect of bovine serum albumin (BSA) on human liver metabolism, in vitro, of 14C-phenytoin (PHT) was studied. Michaelis Menten parameters were determined for the conversion of PHT to p-hydroxy phenytoin in seven different microsomal preparations
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3391bf28a40f4069a7e4183a9650c2e
https://pubmed.ncbi.nlm.nih.gov/9223579
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