Zobrazeno 1 - 10
of 377
pro vyhledávání: '"J M, Seyer"'
Publikováno v:
The Journal of Immunology. 153:824-832
Autoimmune arthritis can be induced in rats by immunization with cartilage-specific types II and XI collagen. Type XI collagen is composed of alpha 1(XI), alpha 2(XI), and alpha 3(XI) chains, in which alpha 3(XI) is essentially identical to alpha 1(I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac10b4e62623d492a1cf94af2a3b2f6
https://doi.org/10.4049/jimmunol.153.2.824
https://doi.org/10.4049/jimmunol.153.2.824
Publikováno v:
The Journal of Immunology. 151:500-505
Chick type II collagen (CII), a protein commonly found in joint cartilage, induces an autoimmune arthritis when administered to susceptible strains of mice. A cyanogen bromide fragment of CII, CB11, contains the requisite epitopes critical for induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39952d05c6f9e324810ff21fb4f82054
https://doi.org/10.4049/jimmunol.151.1.500
https://doi.org/10.4049/jimmunol.151.1.500
Publikováno v:
The Journal of Immunology. 150:4652-4658
The immunization of genetically susceptible strains of mice with type II collagen (CII) elicits a collagen-induced arthritis that resembles rheumatoid arthritis. Our laboratory previously identified a region of CII, CII-245-270, that contains a T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635aa823060165160315441263ed7eaf
https://doi.org/10.4049/jimmunol.150.10.4652
https://doi.org/10.4049/jimmunol.150.10.4652
Publikováno v:
The Journal of Immunology. 149:1439-1443
A synthetic peptide representing sequences of type II collagen, (CII 245-270), has previously been used to induce tolerance and suppress arthritis in DBA/1 mice. To determine important residues, a series of peptides, each containing one or two site-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c114a32ad7017ef7677712c16f1ec6
https://doi.org/10.4049/jimmunol.149.4.1439
https://doi.org/10.4049/jimmunol.149.4.1439
Autor:
W C, Kouns, P J, Newman, K J, Puckett, A A, Miller, C D, Wall, C F, Fox, J M, Seyer, L K, Jennings
Publikováno v:
Blood. 78:3215-3223
Glycoprotein (GP) IIb-IIIa serves as the platelet fibrinogen receptor. Studies of the tertiary structure of GPIIIa have shown that the protein has a large loop structure of at least 325 amino acids in length. To further characterize this loop structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e10f6c53e6b1a74888c0f76c290bf6
https://doi.org/10.1182/blood.v78.12.3215.3215
https://doi.org/10.1182/blood.v78.12.3215.3215
Publikováno v:
The Journal of Immunology. 146:4130-4137
To determine whether native bovine type XI collagen (BXI) is arthritogenic, five strains of inbred mice were immunized with BXI/CFA. Arthritis was not observed in any of these strains, though it was prevalent in DBA/1 and B10.RIII controls immunized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcbcb613ed30a60ea8d7a490d8dbb256
https://doi.org/10.4049/jimmunol.146.12.4130
https://doi.org/10.4049/jimmunol.146.12.4130
Publikováno v:
Arthritis and rheumatism. 43(5)
To determine whether oral tolerance to type I collagen (CI) could be induced in patients with systemic sclerosis (SSc).Twenty adult patients with limited or diffuse SSc were enrolled in a study to receive 0.1 mg of solubilized native bovine CI daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ddfb7140bcfac3142ba4c894d3076e0
https://pubmed.ncbi.nlm.nih.gov/10817559
https://pubmed.ncbi.nlm.nih.gov/10817559
Autor:
K M, McKown, L D, Carbone, S B, Kaplan, J A, Aelion, K M, Lohr, M A, Cremer, J, Bustillo, M, Gonzalez, G, Kaeley, E L, Steere, G W, Somes, L K, Myers, J M, Seyer, A H, Kang, A E, Postlethwaite
Publikováno v:
Arthritis and rheumatism. 42(6)
To investigate the efficacy of oral type II collagen (CII) in the treatment of rheumatoid arthritis (RA), when added to existing therapy.Patients with active RA (n = 190) were randomized into a 6-month, double-blind, placebo-controlled trial. Patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::813747bef1d13d6d085d7c96466f7d23
https://pubmed.ncbi.nlm.nih.gov/10366113
https://pubmed.ncbi.nlm.nih.gov/10366113
Publikováno v:
Immunology. 84(4)
Susceptibility to collagen-induced arthritis (CIA), a murine model of autoimmune arthritis, is strongly linked to only two major histocompatibility complex (MHC) haplotypes, H-2q and H-2r. In order to identify the determinants of type II collagen (CI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f65c6bd80fdb0e6aea799e835ca2555e
https://pubmed.ncbi.nlm.nih.gov/7540590
https://pubmed.ncbi.nlm.nih.gov/7540590
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 69(3)
Transforming growth factor beta 1 (TGF beta 1) gene expression is increased in CCl4-injured rat livers. The biologic link of this increase and liver regeneration has not been established.To explore the identity of the TGF beta 1-producing cells in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27aecb81becfceb695f7d31dcf5ee718
https://pubmed.ncbi.nlm.nih.gov/8377471
https://pubmed.ncbi.nlm.nih.gov/8377471