Zobrazeno 1 - 10
of 11
pro vyhledávání: '"J M, Schaus"'
Autor:
L A, Phebus, J M, Schaus
Publikováno v:
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 45
Publikováno v:
European journal of pharmacology. 352(1)
To determine the potency and efficacy of 5-HT1F receptor ligands, a [35S]GTPgammaS binding assay was developed and optimized for the human 5-HT1F receptor. Compounds which are known to be effective in the abortive treatment of migraine were tested fo
Autor:
M L, Cohen, W, Bloomquist, J M, Schaus, D C, Thompson, A D, Susemichel, D A, Calligaro, I, Cohen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(1)
Although many 5-HT (serotonin, 5-hydroxytryptamine)(4) receptor antagonists have been described, none possess the requisite oral activity and duration of action for a clinically effective therapeutic agent. The present report identifies LY353433 (1-(
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 274(3)
Quinelorane is a BCD partial ergoline with potent dopaminergic effects in vitro and in vivo. Partial ergoline compounds of this series consist of the B-, C- and D-rings of the four ring ergoline skeleton. Many of the pharmacological effects of quinel
Autor:
J M, Schaus, E C, Kornfeld, R D, Titus, C L, Nichols, D L, Huser, J A, Clemens, E B, Smalstig, R W, Fuller
Publikováno v:
Drug design and discovery. 9(3-4)
Ergot alkaloids and their derivatives have long been recognized for their potent pharmacologic activity. A number of ergot derivatives, including the dopamine agonists bromocriptine and pergolide, are currently in clinical use for the treatment of CN
Autor:
M M, Foreman, R W, Fuller, M D, Hynes, J S, Gidda, C L, Nichols, J M, Schaus, E C, Kornfeld, J A, Clemens
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 250(1)
Quinelorane (LY163502) has the endocrine, neurochemical and behavioral profile of a potent and highly selective D2-dopaminergic agonist. The administration of quinelorane produced dose-related decreases in serum prolactin concentration of reserpinize
ChemInform Abstract: GENERAL METHODOLOGY FOR CIS-HYDROISOQUINOLINE SYNTHESIS: SYNTHESIS OF RESERPINE
Publikováno v:
Chemischer Informationsdienst. 11
Publikováno v:
Chemischer Informationsdienst. 15
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