Zobrazeno 1 - 10
of 11
pro vyhledávání: '"J M, Reno"'
Autor:
Lisa Prichard, William P. Schiemann, Lowell H. Ericsson, Robin M. Gibson, J. M. Reno, Neil M. Nathanson
Publikováno v:
Journal of Biological Chemistry. 275:22574-22582
The receptor for leukemia inhibitory factor (LIF) consists of two polypeptides, the LIF receptor and gp130. Agonist stimulation has been shown previously to cause phosphorylation of gp130 on serine, threonine, and tyrosine residues. We found that gp1
Publikováno v:
The Journal of biological chemistry. 275(29)
The receptor for leukemia inhibitory factor (LIF) consists of two polypeptides, the LIF receptor and gp130. Agonist stimulation has been shown previously to cause phosphorylation of gp130 on serine, threonine, and tyrosine residues. We found that gp1
Autor:
H B, Breitz, P L, Weiden, P L, Beaumier, D B, Axworthy, C, Seiler, F M, Su, S, Graves, K, Bryan, J M, Reno
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 41(1)
Pretargeted radioimmunotherapy (PRIT) was evaluated using an antibody-streptavidin conjugate, followed by a biotin-galactose-human serum albumin clearing agent and 90Y-dodecane tetraacetic acid (DOTA)-biotin as the final step for therapy. The objecti
Autor:
S S, Graves, S C, Goshorn, D M, Stone, D B, Axworthy, J M, Reno, B, Bottino, S, Searle, A, Henry, J, Pedersen, A R, Rees, R T, Libby
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(4)
A mouse-human chimeric monoclonal antibody (chNR-LU-13), specific for the EGP40 pancarcinoma antigen, was humanized through three-dimensional molecular modeling. Humanization of the chNR-LU-13 antibody is expected to enhance its use for patients unde
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 33(12)
We evaluated the efficacy of murine monoclonal antibodies (Mabs) targeted to beta/A4 amyloid for development of procedures for the in vivo identification of amyloid angiopathy (AA) in Alzheimer's disease (AD). Mabs to beta/A4 amyloid were prepared an
Autor:
S, Kasina, T N, Rao, A, Srinivasan, J A, Sanderson, J N, Fitzner, J M, Reno, P L, Beaumier, A R, Fritzberg
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 32(7)
A kit has been developed for 99mTc antibody radiolabeling via defined chemistry using an N2S2 diamide dimercaptide bifunctional chelating agent and the performed chelate method. The process involved efficient transchelation of 99mTc from gluconate to
Autor:
J. M. Reno
Publikováno v:
Nuclear Medicine Communications. 18:979
Autor:
Paul L. Beaumier, Wilbur Ds, J A Sanderson, Alton C. Morgan, T.N. Rao, A. R. Fritzberg, Sudhakar Kasina, P G Abrams, A. Srinivasan, J. M. Reno
Publikováno v:
Proceedings of the National Academy of Sciences. 85:4025-4029
Technetium-99m labeling of antibodies has been suboptimal because of low affinity adventitious binding, nonspecific labeling, and loss of immunoreactivity. The diamide dithiolate ligand system (N2S2) forms highly stable, well-defined tetradentate com
Autor:
D S, Wilbur, S W, Hadley, M D, Hylarides, P G, Abrams, P A, Beaumier, A C, Morgan, J M, Reno, A R, Fritzberg
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 30(2)
A method of radioiodinating monoclonal antibodies such that the labeled antibodies do not undergo in vivo deiodination has been studied. The method utilizes conjugation of succinimidyl para-iodobenzoate to the antibody. The iodobenzoate was radiolabe
Publikováno v:
American Nurses Association Publications. (CH-13)