Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J M, Paranjape"'
Autor:
M J, de Veer, M, Holko, M, Frevel, E, Walker, S, Der, J M, Paranjape, R H, Silverman, B R, Williams
Publikováno v:
Journal of leukocyte biology. 69(6)
Interferons (IFNs) are a family of multifunctional cytokines that activate transcription of subsets of genes. The gene products induced by IFNs are responsible for IFN antiviral, antiproliferative, and immunomodulatory properties. To obtain a more co
Autor:
A, Maran, C F, Waller, J M, Paranjape, G, Li, W, Xiao, K, Zhang, M E, Kalaycio, R K, Maitra, A E, Lichtin, W, Brugger, P F, Torrence, R H, Silverman
Publikováno v:
Blood. 92(11)
We report an RNA targeting strategy, which selectively degrades bcr/abl mRNA in chronic myelogenous leukemia (CML) cells. A 2', 5'-tetraadenylate activator (2-5A) of RNase L was chemically linked to oligonucleotide antisense directed against either t