Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J M, Paramio"'
Autor:
I. Lodewijk, A. Bernardini, C. Suárez-Cabrera, E. Bernal, R. Sánchez, J. L. Garcia, K. Rojas, L. Morales, S. Wang, X. Han, M. Dueñas, J. M. Paramio, L. Manso
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-11 (2022)
Abstract Platinum-based neoadjuvant chemotherapy followed by interval debulking surgery is an accepted treatment for patients with stage III or IV epithelial ovarian cancer who are not suitable for primary debulking surgery. The identification of sui
Externí odkaz:
https://doaj.org/article/5a6808a2956b4eb4a805fa9f87f5b57e
Autor:
I. Lodewijk, A. Bernardini, C. Suárez-Cabrera, E. Bernal, R. Sánchez, J. L. Garcia, K. Rojas, L. Morales, S. Wang, X. Han, M. Dueñas, J. M. Paramio, L. Manso
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 6, Iss 1, Pp 1-11 (2022)
Scientia
npj Precision Oncology, Vol 6, Iss 1, Pp 1-11 (2022)
Scientia
Ovarian cancer Càncer d'ovari Cáncer de ovario Platinum-based neoadjuvant chemotherapy followed by interval debulking surgery is an accepted treatment for patients with stage III or IV epithelial ovarian cancer who are not suitable for primary debu
Autor:
M, Moral, J M, Paramio
Publikováno v:
Histology and histopathology. 23(10)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common form of cancer worldwide. One frequent alteration found in this type of cancer is overactivation of the PI3K/PTEN/mTOR pathway, of which protein kinase B (PKB)/Akt is a central ke
Autor:
J M, Paramio, C, Segrelles, S, Ruiz, J, Martin-Caballero, A, Page, J, Martinez, M, Serrano, J L, Jorcano
Publikováno v:
The Journal of biological chemistry. 276(47)
In mammalian cells, cell cycle withdrawal is a prerequisite for terminal differentiation. Accordingly, in most tissues, including epidermis, the expression of the cyclin-dependent kinase inhibitors increases during differentiation. However, the actua
Autor:
J M, Paramio, J L, Jorcano
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 161
Publikováno v:
Molecular carcinogenesis. 29(4)
The p53 phosphoprotein acts as a tumor-suppressor gene product through the inhibition of cell growth and induction of apoptosis in a transcription-dependent manner. These functions require p53 activation through different biochemical postranslational
Autor:
J M, Paramio, J L, Jorcano
Publikováno v:
The British journal of dermatology. 137(1)
Different chemicals that specifically and selectively inhibit or activate protein kinases have been used to define the possible roles of these enzymes in the different steps of epidermal differentiation. Using HaCaT keratinocytes as a model, and unde