Výsledky vyhledávání - "J M, Mansfield"

Akademický článek

Immune Response in Cattle Trypanosomosis and Trypanotolerance: Main Findings and Gaps.

Autor: Somé GF; Centre International de Recherche-Développement Sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France., Séré M; Centre International de Recherche-Développement Sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Université Daniel-Ouezzin-COULIBALLY, Dédougou, Burkina Faso., Somda BM; Centre International de Recherche-Développement Sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso.; Université Nazi BONI, Bobo-Dioulasso, Burkina Faso., Dayo GK; Centre International de Recherche-Développement Sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso., Ouédraogo GA; Université Nazi BONI, Bobo-Dioulasso, Burkina Faso., Boulangé A; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France., Maarifi G; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France., Chantal I; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France., Berthier-Teyssedre D; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France., Thévenon S; Cirad, UMR INTERTRYP, Montpellier, France.; INTERTRYP, Université de Montpellier, Cirad, IRD, Montpellier, France.

Publikováno v: Parasite immunology [Parasite Immunol] 2024 Nov; Vol. 46 (11), pp. e13075.

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Trypanosome variant surface glycoproteins are recognized by self-reactive antibodies in uninfected hosts

Autor: Thomas Seebeck, Norbert Müller, J. M. Mansfield

Publikováno v: Infection and Immunity. 64:4593-4597

The variant surface glycoproteins (VSGs) of African trypanosomes form a dense surface coat on the bloodstream parasites. VSGs are immunodominant antigens that stimulate a rapid antibody response in trypanosome-infected individuals. In the present stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17468650cf629048e0f9a231a737dbcb
https://doi.org/10.1128/iai.64.11.4593-4597.1996

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Suppressor macrophages in African trypanosomiasis inhibit T cell proliferative responses by nitric oxide and prostaglandins

Autor: K W Schleifer, J M Mansfield

Publikováno v: The Journal of Immunology. 151:5492-5503

Suppression of host T cell responses is one of the hallmarks of infection with the African trypanosomes. The cellular basis for immunosuppression includes the generation of suppressor macrophages that down-regulate T cell proliferative but not necess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e5d6ceffceee988121661922a1ea2b3
https://doi.org/10.4049/jimmunol.151.10.5492

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Characterization of T helper cell responses to the trypanosome variant surface glycoprotein

Autor: K W Schleifer, H Filutowicz, L R Schopf, J M Mansfield

Publikováno v: The Journal of Immunology. 150:2910-2919

T cell responses to the variant surface glycoprotein (VSG) previously have not been detected in animals infected with the African trypanosomes despite the fact that such animals make strong T-dependent B cell responses to VSG molecules displayed by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34a3f1363de0ed6dd68907c487cf8edb
https://doi.org/10.4049/jimmunol.150.7.2910

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Regulation of B cell responses to the variant surface glycoprotein molecule in trypanosomiasis. II. Down-regulation of idiotype expression is associated with the appearance of lymphocytes expressing antiidiotypic receptors

Autor: C M Theodos, J M Mansfield

Publikováno v: The Journal of Immunology. 144:4022-4029

The current study examines the idiotypic expression and regulation of variant surface glycoprotein (VSG)-specific B cell responses during African trypanosomiasis. Utilizing competitive inhibition RIA analysis, we detected antibodies in the serum of B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7425e3fc9d5767c37c7421c2b1150878
https://doi.org/10.4049/jimmunol.144.10.4022

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Resistance to the African trypanosomes is IFN-gamma dependent

Autor: C J, Hertz, H, Filutowicz, J M, Mansfield

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(12)

The role of variant surface glycoprotein (VSG)-specific Th cell responses in determining resistance to the African trypanosomes was examined by comparing Th cell responses in relatively resistant and susceptible mice as well as in cytokine gene knock

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0379e0c56788a63dd4b53881e50099c0
https://pubmed.ncbi.nlm.nih.gov/9862708

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Characterization of a relatively rare class B, type 2 trypanosome variant surface glycoprotein gene

Autor: L R, Schopf, J M, Mansfield

Publikováno v: The Journal of parasitology. 84(2)

The variant surface glycoprotein (VSG) gene of Trypanosoma brucei rhodesiense LouTat 1.5, a defined African trypanosome variant antigenic type, was cloned and sequenced. Southern blot analysis revealed 2 DNA restriction fragments in both VSG 1.5 expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b27115240314e5e1dff157e35cabb8d1
https://pubmed.ncbi.nlm.nih.gov/9576500

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