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2-Aminopurine Overrides a Late Telophase Delay Created by Ectopic Expression of the PITSLREβ1 Protein Kinase

Autor: V. J. Kidd, J. M. Lahti, Jialing Xiang

Publikováno v: Biochemical and Biophysical Research Communications. 199:1167-1173

Minimal overexpression of the PITSLRE beta 1 protein kinase in CHO cells leads to a marked delay in late mitosis. We have previously shown that this delay is characterized by the presence of substantially increased numbers of tubulin midbodies, inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6135af3a006f35db55509d95c351c2
https://doi.org/10.1006/bbrc.1994.1353

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Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases

Autor: M E, Ariza, M, Broome-Powell, J M, Lahti, V J, Kidd, M A, Nelson

Publikováno v: The Journal of biological chemistry. 274(40)

The Cdc2L locus encoding the PITSLRE protein kinases maps to chromosome band 1p36 and consists of two duplicated and tandemly linked genes. The purpose of the present study was to determine whether diminution of PITSLRE kinases leads to deregulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::61612a858476ced666ee9e702e1e1466
https://pubmed.ncbi.nlm.nih.gov/10497214

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Disruption of the cyclin D/cyclin-dependent kinase/INK4/retinoblastoma protein regulatory pathway in human neuroblastoma

Autor: J, Easton, T, Wei, J M, Lahti, V J, Kidd

Publikováno v: Cancer research. 58(12)

The p16INK4a (MTS1) and pl8INK4c gene products are normal, and highly expressed, in human neuroblastoma cell lines. The retinoblastoma protein (pRb) was, nonetheless, phosphorylated and functional in these cells. Such high levels of p16INK4a/p18INK4c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ee39806c6fbe2a775d48ae9c953a86b1
https://pubmed.ncbi.nlm.nih.gov/9635589

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Mapping of five members of the cyclin gene family on chicken chromosomes by FISH

Autor: J, Masabanda, R, Friedl, A, Sazanov, J M, Lahti, H, Li, V J, Kidd, R, Fries

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 6(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7007def6cf0979d4d0aa32f8c58f41e8
https://pubmed.ncbi.nlm.nih.gov/9609667

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Alternatively spliced cyclin C mRNA is widely expressed, cell cycle regulated, and encodes a truncated cyclin box

Autor: H, Li, J M, Lahti, V J, Kidd

Publikováno v: Oncogene. 13(4)

The cyclin C protein has recently been shown to associate with a unique cyclin dependent protein kinase (cdk8) and it has been proposed that this complex may regulate RNA transcription during the cell cycle. In addition, the human cyclin C gene has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03a014aa06aca53fe5ab5b942fee6683
https://pubmed.ncbi.nlm.nih.gov/8761291

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Laser light suicide of proliferating virus-specific CD8+ T cells in an in vivo response

Autor: R A, Tripp, J M, Lahti, P C, Doherty

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 155(8)

Virus-specific CD8+ CTL precursor (CTLp) frequencies are a function of rates of clonal expansion and loss, both of which are difficult to assess in vivo. Proliferating T cells incorporate the nucleoside analogue 5-bromo-2'-deoxyuridine (BrdU), making

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bcbf1cc9f71f20825e5ca51f1c7ca164
https://pubmed.ncbi.nlm.nih.gov/7561074

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The PITSLRE protein kinase family

Autor: J M, Lahti, J, Xiang, V J, Kidd

Publikováno v: Progress in cell cycle research. 1

A family of p34Cdc2 related protein kinases, the PITSLRE kinases, is generated by alternative splicing and promoter utilization from three duplicated and tandemly linked genes on human chromosome 1p36.3, which is frequently deleted during the late st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::327cad87c6448e791bbcbc935ce558bd
https://pubmed.ncbi.nlm.nih.gov/9552375

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Autor: J M, Lahti, J, Xiang, V J, Kidd

Publikováno v: Advances in experimental medicine and biology. 376

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efb3dfe83555d4043795315e21210708
https://pubmed.ncbi.nlm.nih.gov/8597255

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T-cell development in birds

Autor: D. Char, R. P. Bucy, Max D. Cooper, J. M. Lahti, C H Chen, James F. George

Publikováno v: Cold Spring Harbor symposia on quantitative biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dd79920e10be5699b5849a3e057d44
https://pubmed.ncbi.nlm.nih.gov/2534800

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Ontogeny of T Cells and a Third Lymphocyte Lineage in the Chicken

Autor: U. Lösch, J. M. Lahti, David Char, P. Sanchez, M Coltey, C H Chen, James F. George, N. M. Le Douarin, R. P. Bucy, J. Cihak, Max D. Cooper

Publikováno v: Progress in Immunology ISBN: 9783642837579

Comparative analysis of immune system development in birds and mammals revealed that development of lymphoid stem cells proceeds along T and B cell lines (Cooper et al. 1965; Moore and Owen 1967). In order to begin T cell development, blood-borne ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5da511df9b15cfeaa2971b0213bfe5a0
https://doi.org/10.1007/978-3-642-83755-5_31

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