Zobrazeno 1 - 10 of 71 pro vyhledávání: '"J M, Hershman"'
1
Divergent dimerization properties of mutant beta 1 thyroid hormone receptors are associated with different dominant negative activities
Autor: J B Menke, C Jones, Stephen J. Usala, H H Samuels, Mitchell E. Geffner, A M Smith, E Hao, J P Wuerth, D K Ways, J M Hershman
Publikováno v: Molecular Endocrinology. 8:841-851
Syndromes of resistance to thyroid hormones are caused by mutations in the T3-binding domain of the c-erbA beta thyroid hormone receptor gene. The S receptor (deletion of THR332) is a potent dominant negative protein cloned from a kindred with genera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3a37d6b719c0a17d5c2a6f41d0d962
https://doi.org/10.1210/mend.8.7.7984146
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2
Tumor necrosis factor-alpha activates nuclear factor kappa B and induces manganous superoxide dismutase and phosphodiesterase mRNA in human papillary thyroid carcinoma cells
Autor: J. M. Hershman, N. S. Ross, Xuan-Ping Pang, M. Park, G. J. F. Juillard, T. M. Stanley
Publikováno v: Journal of Biological Chemistry. 267:12826-12830
Human papillary thyroid carcinoma (PTC) has a relatively benign prognosis despite a high frequency of lymphatic metastasis. This suggests that local anticancer factors, generated in lymph nodes, control PTC progression. The cytokine, tumor necrosis f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebf96eec502844372f335a042501518c
https://doi.org/10.1016/s0021-9258(18)42350-2
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3
Lithium-induced subclinical hypothyroidism: review of the literature and guidelines for treatment
Autor: J, Kleiner, L, Altshuler, V, Hendrick, J M, Hershman
Publikováno v: The Journal of clinical psychiatry. 60(4)
This review addresses the definition, prevalence, etiology, and clinical significance of lithium-associated subclinical hypothyroidism and offers guidelines for evaluation and treatment of this condition.MEDLINE was used to search all articles writte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a85f62f28802bd9b932e5b6eb8d9e4cd
https://pubmed.ncbi.nlm.nih.gov/10221287
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4
Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I- symporter messenger ribonucleic acid levels in FRTL-5 cells
Autor: A E, Pekary, J M, Hershman
Publikováno v: Endocrinology. 139(2)
Iodide uptake, which is necessary for thyroid hormone synthesis, can be inhibited by aging, withdrawal of TSH, or increased tumor necrosis factor (TNF) and transforming growth factor (TGF)-beta1 levels resulting from the nonthyroid illness syndrome.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::533cdec666b5093c399282c10b8b1ab0
https://pubmed.ncbi.nlm.nih.gov/9449644
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5
Growth inhibition of new human thyroid carcinoma cell lines by activation of adenylate cyclase through the beta-adrenergic receptor
Autor: K, Ohta, X P, Pang, L, Berg, J M, Hershman
Publikováno v: The Journal of clinical endocrinology and metabolism. 82(8)
In normal thyroid cells, the TSH-adenylate cyclase system plays a pivotal role in controlling growth and differentiation. However, the role of this system in the growth of thyroid carcinoma is not well understood. To investigate this subject, we have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::900d1195011a3ae2289d2043e280fd56
https://pubmed.ncbi.nlm.nih.gov/9253346
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7
Tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta 1 (TGF-beta 1) inhibit the expression and activity of Na+/K(+)-ATPase in FRTL-5 rat thyroid cells
Autor: A E, Pekary, S R, Levin, D G, Johnson, L, Berg, J M, Hershman
Publikováno v: Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 17(4)
We recently reported that tumor necrosis factor-alpha (TNF-alpha) induction of the synthesis and secretion of transforming growth factor (TGF)-beta 1 by FRTL-5 cells is a thyroid-stimulating hormone (TSH)-dependent and age-dependent process. TNF-alph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1fa1232141751f966d638f0a937ae7c
https://pubmed.ncbi.nlm.nih.gov/9142647
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9
TNF-alpha induction of A1 expression in human cancer cells
Autor: X P, Pang, J M, Hershman, A, Karsan
Publikováno v: Oncology research. 9(11-12)
A1, a member of the Bcl-2 gene family, was originally identified as a hemopoietic-specific early response gene. Later it was found that A1 was overexpressed in human stomach cancer tissues and was induced by tumor necrosis factor-alpha (TNF-alpha) in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5493a80d8910d27aeac50acb1997cf21
https://pubmed.ncbi.nlm.nih.gov/9563010
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10
Endocrine effects of erythropoietin
Autor: H E, Carlson, M L, Graber, M C, Gelato, J M, Hershman
Publikováno v: The International journal of artificial organs. 18(6)
Uremic men may manifest a variety of hormonal abnormalities, including decreased serum concentrations of testosterone and thyroid hormones and increased serum levels of growth hormone and prolactin. Some previous investigations have reported that ery
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db8b21a63302d00cc7d5676b0b7b22c1
https://pubmed.ncbi.nlm.nih.gov/8593965
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