The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia

Autor: C S, Chen, J M, Hilden, J, Frestedt, P H, Domer, R, Moore, S J, Korsmeyer, J H, Kersey

Publikováno v: Blood. 82:1080-1085

The chromosomal translocation, t(4;11)(q21;q23), is the most common type of 11q23 chromosomal abnormality, being highly prevalent in infant acute leukemias and associated with a poor prognosis. The t(4;11) results in the fusion of an 11q23 gene (MLL,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e2f6ed412f6930231d1bf524b53f5c
https://doi.org/10.1182/blood.v82.4.1080.bloodjournal8241080

Misleading leads: Wilms tumor with a metachronous lesion appearing in the remaining kidney

Autor: J M, Hilden, W S, Brennom, J J, Wolpert, J B, Beckwith

Publikováno v: Medical and pediatric oncology. 30(3)

Medullary dysplasia may be present in the kidneys of children with the Beckwith-Wiedemann Syndrome (BWS). This is usually visible only at the microscopic level, but superimposed pyelonephritis in a child with the BWS led to gross changes that produce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f645509e0d3ceadce4a768a836b543f9
https://pubmed.ncbi.nlm.nih.gov/9434829

Molecular analysis of infant acute lymphoblastic leukemia: MLL gene rearrangement and reverse transcriptase-polymerase chain reaction for t(4; 11)(q21; q23)

Autor: J M, Hilden, J L, Frestedt, R O, Moore, N A, Heerema, D C, Arthur, G H, Reaman, J H, Kersey

Publikováno v: Blood. 86(10)

Molecular techniques to detect MLL (11q23) and AF-4 (4q21) gene rearrangements are being evaluated for use in stratification of patients into prognostic groups. We studied 15 cases of infant acute lymphoblastic leukemia (ALL) with Southern blotting f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d992312b519311c9669e082957ac188
https://pubmed.ncbi.nlm.nih.gov/7579356

#614 Transient monosomy 7 in children. A case series

Autor: D. A. Singer, J. M. Hilden, J. Finklestein, E. Sandler, K. W. Chan, K. M. Shannon, E. Mantadakis

Publikováno v: Journal of Pediatric Hematology/Oncology. 20:377

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e05a20138876fb87edfe86d0fc18f78c
https://doi.org/10.1097/00043426-199807000-00051

Rhabdoid Tumor of the Kidney and Soft Tissues: Results from National Wilms Tumor Study-5 and Children's Oncology Group Study AREN0321.

Autor: Geller JI; Division of Pediatric Oncology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio, USA., Renfro LA; Division of Biostatistics, University of Southern California and Children's Oncology Group, Los Angeles, California, USA., Grundy PE; Division of Immunology, Hematology, Oncology, Palliative Care, and Environmental Interactions, University of Alberta, Edmonton, Alberta, Canada., Perlman EJ; Department of Pathology and Laboratory Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Kalapurakal JA; Department of Radiation Oncology, Northwestern University, Chicago, Illinois, USA., Ehrlich PF; Section of Pediatric Surgery, CS Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA., Biegel J; Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA., Huff V; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Warwick AB; Department of Pediatrics, F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, Maryland, USA., Paulino A; MD Anderson Cancer Center, Houston, Texas, USA., Mullen EA; Boston Children's Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA., Daw NC; Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hoffer FA; Department of Radiology, Fred Hutchison Cancer Center, University of Washington, Seattle, Washington, USA., Tochner Z; Department of Radiation Oncology, Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Gow K; Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA., Gratias E; eviCore Healthcare, Bluffton, South Carolina, USA., Ward DA; Department of Pharmaceutical Services, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Anderson JR; University of Nebraska Medical Center, Omaha, Nebraska, USA., Fernandez CV; Division of Pediatric Hematology Oncology, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada., Dome JS; Division of Oncology, Children's National Hospital and Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Dec 19, pp. e31490. Date of Electronic Publication: 2024 Dec 19.