The ligand binding site of the formyl peptide receptor maps in the transmembrane region

Autor: H M, Miettinen, J S, Mills, J M, Gripentrog, E A, Dratz, B L, Granger, A J, Jesaitis

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(8)

We propose that the N-formyl-Met-Leu-Phe binding site in the human neutrophil formyl peptide receptor (FPR) lies in the predicted transmembrane region. We examined the expression, binding, and G protein coupling of 28 mutated forms of FPR in stably t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68d549afb3cbb2ed37f33ee7e6081a32
https://pubmed.ncbi.nlm.nih.gov/9378994

Targeting Ligand Independent Tropism of siRNA-LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells.

Autor: Lin C; Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.; Department of Rheumatology and Shanghai Institute of Rheumatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China., Jans A; Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany., Wolters JC; Department of Pediatrics, Section Systems Medicine of Metabolism and Signaling, University of Groningen, University Medical Center Groningen, Groningen, 9713 AV, The Netherlands., Mohamed MR; Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany., Van der Vorst EPC; Interdisciplinary Center for Clinical Research (IZKF), RWTH Aachen University, 52074, Aachen, Germany.; Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, 52074, Aachen, Germany.; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, 80336, Munich, Germany., Trautwein C; Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany., Bartneck M; Department of Internal Medicine III, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Oct; Vol. 13 (26), pp. e2202670. Date of Electronic Publication: 2023 Jan 08.

Neutrophil and Nanoparticles Delivery to Tumor: Is It Going to Carry That Weight?

Autor: Vishnevskiy DA; V. Serbsky National Medical Research Center for Psychiatry and Narcology, Kropotkinskiy Pereulok, 23, Moscow, 119034, Russia.; N. I Pirogov Russian National Research Medical University, Ulitsa Ostrovityanova, 1, Moscow, 117997, Russia., Garanina AS; National University of Science and Technology (MISIS), Leninskiy Prospekt, 4, Moscow, 119049, Russia., Chernysheva AA; V. Serbsky National Medical Research Center for Psychiatry and Narcology, Kropotkinskiy Pereulok, 23, Moscow, 119034, Russia., Chekhonin VP; V. Serbsky National Medical Research Center for Psychiatry and Narcology, Kropotkinskiy Pereulok, 23, Moscow, 119034, Russia.; N. I Pirogov Russian National Research Medical University, Ulitsa Ostrovityanova, 1, Moscow, 117997, Russia., Naumenko VA; V. Serbsky National Medical Research Center for Psychiatry and Narcology, Kropotkinskiy Pereulok, 23, Moscow, 119034, Russia.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2021 May; Vol. 10 (9), pp. e2002071. Date of Electronic Publication: 2021 Mar 18.

Variable responses of formyl peptide receptor haplotypes toward bacterial peptides.

Autor: Gripentrog, Jeannie M., Mills, John S., Saari, George J., Miettinen, Heini M.

Publikováno v: Immunogenetics; Feb2008, Vol. 60 Issue 2, p83-93, 11p, 1 Diagram, 2 Charts, 3 Graphs

Mutations in the NPxxY motif stabilize pharmacologically distinct conformational states of the α1B- and β2-adrenoceptors.

Autor: Ragnarsson, Lotten, Andersson, Åsa, Thomas, Walter G., Lewis, Richard J.

Publikováno v: Science Signaling; 3/12/2019, Vol. 12 Issue 572, pN.PAG-N.PAG, 1p