Výsledky vyhledávání - "J M, Freyssinet"

Les microparticules circulantes : rôles physiologiques et implications dans les maladies inflammatoires et thrombotiques

Autor: Florence Toti, O. Morel, N. Morel, Bernard Goichot, B. Bakouboula, Stéphane Vinzio, B. Hugel, Lelia Grunebaum, J M Freyssinet, Laurence Jesel

Publikováno v: La Revue de Médecine Interne. 26:791-801

Resume Propos. – L'apoptose est un processus fondamental a l'homeostasie des organismes pluricellulaires en permettant l'elimination des cellules senescentes. Longtemps considerees comme des debris cellulaires depourvus de fonction biologique propr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b9a95ecabe63b749a167a16987a327ad
https://doi.org/10.1016/j.revmed.2005.03.015

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Circulating Procoagulant Microparticles in Women with Unexplained Pregnancy Loss: a New Insight

Autor: Bénédicte Hugel, J M Freyssinet, V. Eschwège, V. Mairovitz, R. Frydman, Martine Wolf, Dominique Meyer, C. Rongières-Bertrand, Catherine Boyer-Neumann, I. Laude

Publikováno v: Thrombosis and Haemostasis. 85:18-21

SummaryOne of the frequently proposed mechanisms for pregnancy losses refers to uteroplacental thrombosis. However the contribution of classical thrombotic risk factors remains questionable and, if real, does not account for a large number of pregnan

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https://doi.org/10.1055/s-0037-1612657

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Apoptosis in Vascular Disease

Autor: Dominique Meyer, Gidon-Jeangirard C, Corinne Kunzelmann, Florence Toti, J M Freyssinet, Martínez Mc, Bénédicte Hugel

Publikováno v: Thrombosis and Haemostasis. 82:727-735

IntroductionApoptosis, the term introduced 27 years ago to characterize a particular form of cell death distinct from necrosis,1 is now considered a genetically-controlled and energy-dependent process of fundamental significance in the development an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78047c15242c593d5854ca5a9c2aaf65
https://doi.org/10.1055/s-0037-1615904

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Monocyte vesiculation is a possible mechanism for dissemination of membrane-associated procoagulant activities and adhesion molecules after stimulation by lipopolysaccharide

Autor: N Satta, F Toti, O Feugeas, A Bohbot, J Dachary-Prigent, V Eschwège, H Hedman, J M Freyssinet

Publikováno v: The Journal of Immunology. 153:3245-3255

Endotoxin-stimulated monocytes can elicit a dual procoagulant response. They express tissue factor and expose phosphatidylserine in the outer leaflet of the plasma membrane. Tissue factor, a membrane glycoprotein, is the cellular trigger of blood coa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::371dfe99f0946ca7fe9468032c8f0e60
https://doi.org/10.4049/jimmunol.153.7.3245

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Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester

Autor: Alain Beretz, G Archipoff, J P Cazenave, J M Freyssinet, Christine Brisson, C Klein-Soyer

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 1991, 273, pp.679-684

Thrombomodulin and tissue-factor activities were measured on the surface of confluent human saphenous-vein endothelial cells (HSVEC) cultivated in 96-multiwell plates. Thrombomodulin activity was measured in the presence of purified human thrombin (2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55755a3814a1174cef91862524ff156d
https://doi.org/10.1042/bj2730679

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Antithrombin Vicenza, Ala 384 to Pro (GCA to CCA) mutation, transforming the inhibitor into a substrate

Autor: R. Caso, D. A. Lane, E. A. Thompson, R. J. Olds, S. L. Thein, M. Panico, I. Blench, H. R. Morris, J. M. Freyssinet, M. Aiach, F. Rodeghiero and, G. Finazzi

Publikováno v: British Journal of Haematology. 77:87-92

Antithrombin (AT) Vicenza has been previously identified as a functionally abnormal antithrombin associated with familial thrombosis (Finazzi et al, 1985). It binds normally to heparin, but loses its affinity following interaction with thrombin: it i

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https://doi.org/10.1111/j.1365-2141.1991.tb07953.x

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Déficits congénitaux dans les systèmes anticoagulants naturels responsables de maladies thromboemboliques récidivantes

Autor: M. L. Wiesel, Lelia Grunebaum, J M Freyssinet, J P Cazenave

Publikováno v: La Revue de Médecine Interne. 12:37-41

Resume Le systeme de la coagulation peut-etre assimile a une succession des reactions enzymatiques, organisees en complexes moleculaires assembles a la surface de la cellule endotheliale ou de la plaquette stimulees. Ces reactions aboutissent a la ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::153b3f8c095b818c3f2c71ce12a8738a
https://doi.org/10.1016/s0248-8663(05)81351-7

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[Markers of thrombotic disease: procoagulant microparticles]

Autor: O, Morel, F, Toti, J-M, Freyssinet

Publikováno v: Annales pharmaceutiques francaises. 65(2)

Thrombosis remains one of the leading causes of mortality and morbidity in developed countries. Relevant markers of the primary thrombotic risk however remain of limited accessibility, and clinicians are left with markers of essentially etiological n

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https://pubmed.ncbi.nlm.nih.gov/17404540

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[Microparticles during sepsis and trauma. A link between inflammation and thrombotic processes]

Autor: N, Morel, O, Morel, X, Delabranche, L, Jesel, F, Sztark, P, Dabadie, J-M, Freyssinet, F, Toti

Publikováno v: Annales francaises d'anesthesie et de reanimation. 25(9)

Sepsis and trauma lead to a sustained activation of monocytes and endothelium. In the vascular compartment, stimulated cells release microparticles. Circulating MP provide an additional procoagulant phospholipid surface enabling the assembly of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f09625483b92c4eb62c2a9179f4761c
https://pubmed.ncbi.nlm.nih.gov/16926090

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