Zobrazeno 1 - 10
of 64
pro vyhledávání: '"J M, Fischer"'
Autor:
Clara Hoebart, Attila Kiss, Bruno K. Podesser, Ammar Tahir, Michael J. M. Fischer, Stefan Heber
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1856 (2024)
Sensory neurons densely innervate the myocardium. The role of their sensing and response to acute and prolonged ischemia is largely unclear. In a cellular model of ischemia-reperfusion injury, the presence of sensory neurons increases cardiomyocyte s
Externí odkaz:
https://doaj.org/article/469a13a58cf1415ba0a0cfae8f9302e2
Autor:
Maximilian L. Mager, Cosmin I. Ciotu, Markus Gold-Binder, Stefan Heber, Michael J. M. Fischer
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and purpose: Addition of preservatives ensures microbial stability, especially in multidose containers of parenterally administered pharmaceuticals. These compounds can cause side effects, and particularly at the site of application, might
Externí odkaz:
https://doaj.org/article/c51bb090e4e2499a9a964c7420623a01
Autor:
Saskia Wedel, Praveen Mathoor, Oliver Rauh, Tim Heymann, Cosmin I. Ciotu, Dominik C. Fuhrmann, Michael J. M. Fischer, Andreas Weigert, Natasja de Bruin, Felix Hausch, Gerd Geisslinger, Marco Sisignano
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Neuropathic pain is experienced worldwide by patients suffering from nerve injuries, infectious or metabolic diseases or chemotherapy. However, the treatment options are still limited because of low efficacy and sometimes severe s
Externí odkaz:
https://doaj.org/article/a1ae3ff5437d4071b8e640f89f13be07
Autor:
Tina Blažević, Cosmin I Ciotu, Markus Gold-Binder, Elke H Heiss, Michael J M Fischer, Verena M Dirsch
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281191 (2023)
We showed previously that capsaicin, an active compound of chili peppers, can inhibit platelet-derived growth factor-induced proliferation in primary rat vascular smooth muscle cells (VSMCs). The inhibition of BrdU incorporation by capsaicin in these
Externí odkaz:
https://doaj.org/article/4bd5b2936b62482d8e4c4cff87d4e85c
Autor:
Tal Hoffmann, Florian Klemm, Tatjana I Kichko, Susanne K Sauer, Katrin Kistner, Bernhard Riedl, Patrick Raboisson, Lei Luo, Alexandru Babes, Laurence Kocher, Giancarlo Carli, Michael J. M. Fischer, Peter W. Reeh
Publikováno v:
Physiological Reports, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract The most widely used formalin test to screen antinociceptive drug candidates is still apostrophized as targeting inflammatory pain, in spite of strong opposing evidence published. In our rat skin‐nerve preparation ex vivo, recording from a
Externí odkaz:
https://doaj.org/article/1914070659d6462b8e34932dd1b49f99
Autor:
Stefan Heber, David Pereyra, Waltraud C. Schrottmaier, Kerstin Kammerer, Jonas Santol, Benedikt Rumpf, Erich Pawelka, Markus Hanna, Alexander Scholz, Markus Liu, Agnes Hell, Klara Heiplik, Benno Lickefett, Sebastian Havervall, Marianna T. Traugott, Matthias J. Neuböck, Christian Schörgenhofer, Tamara Seitz, Christa Firbas, Mario Karolyi, Günter Weiss, Bernd Jilma, Charlotte Thålin, Rosa Bellmann-Weiler, Helmut J. F. Salzer, Gero Szepannek, Michael J. M. Fischer, Alexander Zoufaly, Andreas Gleiss, Alice Assinger
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
ObjectiveTo develop and validate a prognostic model for in-hospital mortality after four days based on age, fever at admission and five haematological parameters routinely measured in hospitalized Covid-19 patients during the first four days after ad
Externí odkaz:
https://doaj.org/article/92908d02a5ae4a5ba5ef80b979f6524a
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Atopic dermatitis (AD) is a multifaceted, chronic relapsing inflammatory skin disease that affects people of all ages. It is characterized by chronic eczema, constant pruritus, and severe discomfort. AD often progresses from mild annoyance to intract
Externí odkaz:
https://doaj.org/article/f9deaccf21b64342a0fc5614adb2601e
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
A fundamental subdivision of nociceptive sensory neurons is named after their unique sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin-sensitive afferents. The initial excitation by capsaicin of these neur
Externí odkaz:
https://doaj.org/article/55042f0450f34077af63a18c5e8b0f71
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 605 (2022)
Background: Preclinical studies suggest that methylglyoxal (MG) increases within the myocardium upon acute myocardial infarction (AMI) and thereafter contributes to adverse postinfarct remodeling. The aims of this study were to test whether MG increa
Externí odkaz:
https://doaj.org/article/18fa1ed0bffb41f2b3202a1b7b8e2b8e
Autor:
Christin Schneider, Lisa Gebhardt, Stephanie Arndt, Sigrid Karrer, Julia L. Zimmermann, Michael J. M. Fischer, Anja-Katrin Bosserhoff
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Cold atmospheric plasma (CAP) is a promising approach in anti-cancer therapy, eliminating cancer cells with high selectivity. However, the molecular mechanisms of CAP action are poorly understood. In this study, we investigated CAP effects o
Externí odkaz:
https://doaj.org/article/d6ac0c68457e4130a56c318724b91166