Zobrazeno 1 - 10
of 16
pro vyhledávání: '"J M, Eisenstadt"'
Autor:
C R Merril, M Chloupkova, S J Zullo, W A Fenton, J M Eisenstadt, W T Parks, Baoxian Wei, Henry Weiner
Publikováno v:
Rejuvenation Research. 8:18-28
Point and deletion mutations and a general depletion of mammalian mitochondrial DNA (mtDNA) give rise to a wide variety of medical syndromes that are refractory to treatment, possibly including aging itself. While gene therapy directed at correcting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1c0d5f80f893693cdf11ec19cc6257
https://doi.org/10.1089/rej.2005.8.18
https://doi.org/10.1089/rej.2005.8.18
Publikováno v:
Journal of molecular biology. 221(4)
We have cloned two fragments of rat nuclear DNA (nucDNA), 3.3 x 10(3) nucleotide-pairs (knp) and 9.1 knp, that contain a 0.5 knp section sharing 80% sequence identity with the mitochondrial DNA (mtDNA) heavy strand origin of replication (D-loop) nasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31bd1897413e6ddc3daf19065bb00c23
https://pubmed.ncbi.nlm.nih.gov/1942048
https://pubmed.ncbi.nlm.nih.gov/1942048
Publikováno v:
Molecular and Cellular Biology. 6:1951-1957
We examined the mitochondrial transcription and translation products of somatic cell hybrids constructed by the fusion of Chinese hamster and mouse cells. The hybrid cell lines OAC-k, OAC-l, and OAC-m contain approximately equal amounts of hamster an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be5e177bae175709f6216023bde95e8
https://doi.org/10.1128/mcb.6.6.1951-1957.1986
https://doi.org/10.1128/mcb.6.6.1951-1957.1986
Autor:
J W Chamberlain, J A Nolan, S H Gromkowski, K A Kelley, J M Eisenstadt, K Herrup, C A Janeway, S M Weissman
Publikováno v:
The Journal of Immunology. 140:1285-1292
We have introduced the gene encoding the heavy chain of the human MHC class I Ag HLA-B7 into transgenic mice. The gene was shown to be expressed at both the RNA and protein level. Cell surface HLA-B7 was detected on whole spleen cells by immunoprecip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b408fc7621caa397066f55ba7371e0
https://doi.org/10.4049/jimmunol.140.4.1285
https://doi.org/10.4049/jimmunol.140.4.1285
Publikováno v:
Proceedings of the National Academy of Sciences. 73:2838-2842
Gene transfer between two closely related mouse cell lines has been carried out, using as the vector a cell-free preparation of metaphase chromosomes and nuclei. Distinction between gene transferents and revertants of the recipient mutant phenotype w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ede04dd099ddaae48dc044d9328f4fa
https://doi.org/10.1073/pnas.73.8.2838
https://doi.org/10.1073/pnas.73.8.2838
Publikováno v:
Molecular and Cellular Biology. 7:2999-3003
The overexpressed A gamma globin gene in the Greek type of nondeletion hereditary persistence of fetal hemoglobin has a unique single-base substitution located at position -117 relative to the site of transcription initiation. This gene and its norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85343ac44fd60a0cf6cfa4b0c673750
https://doi.org/10.1128/mcb.7.8.2999
https://doi.org/10.1128/mcb.7.8.2999
Publikováno v:
Molecular and Cellular Biology. 4:618-624
Hypoxanthine-guanine phosphoribosyltransferase (HPRT) enzyme activities may be elevated in genetically unstable chromosome-mediated gene transferents selected for transfer of the HPRT gene. Increased levels of HPRT polypeptides in unstable mouse L ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc64db15e8eaf0dfa65512c42a1004d
https://doi.org/10.1128/mcb.4.4.618
https://doi.org/10.1128/mcb.4.4.618
Publikováno v:
Proceedings of the National Academy of Sciences. 74:3956-3959
The specific activity of hypoxanthine-guanine phosphoribosyltransferase (IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) is increased up to 58-fold in unstable gene transferents produced by the transfer of cell-free chromosomal material from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7b10d35e09de07842c3502e0b75505
https://doi.org/10.1073/pnas.74.9.3956
https://doi.org/10.1073/pnas.74.9.3956
Publikováno v:
Somatic Cell Genetics. 3:93-119
Cytoplasmically inherited chloramphenicol (CAP) resistance in human cells has been used to study the interaction between sensitive and resistant mitochondria. Cybrids between two HeLa cells were stable for resistance, grew rapidly and cloned well in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08db41332135894804f004095295ad46
https://doi.org/10.1007/bf01550989
https://doi.org/10.1007/bf01550989
Autor:
L. W. Aamodt, J. M. Eisenstadt
Publikováno v:
Journal of Bacteriology. 96:1079-1088
The micro-complement-fixation assay has been demonstrated to be a sensitive assay for flagella which occur in nanogram amounts. By use of this assay, it was found that flagellar synthesis occurs during starvation of Salmonella typhimurium for tryptop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b74fbd162d47a1c61b4c888e390788c
https://doi.org/10.1128/jb.96.4.1079-1088.1968
https://doi.org/10.1128/jb.96.4.1079-1088.1968