Výsledky vyhledávání - "J M, Eckstein"

Comparative intestinal and testes toxicity of four aminothiols in irradiated and nonirradiated mice

Autor: L, Steel-Goodwin, J E, Egan, J M, Kendrick, W E, Jackson, L M, Heman-Ackah, J M, Eckstein

Publikováno v: Annals of clinical and laboratory science. 23(6)

Intestinal and testicular toxicity in groups of nonirradiated and irradiated mice were investigated after intraperitoneal injection of aminothiol compounds or saline. Four aminothiols were studied. Three were prodrugs: WR-2721, WR-3689, and WR-151327

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1b1e6b5f9ef14848759d711010f3892
https://pubmed.ncbi.nlm.nih.gov/8291898

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Pentoxifylline treatment of sepsis in conscious Yucatan minipigs

Autor: W R, Law, V M, Nadkarni, M A, Fletcher, J J, Nevola, J M, Eckstein, J, Quance, T M, McKenna, C H, Lee, T J, Williams

Publikováno v: Circulatory shock. 37(4)

Recent evidence suggests that pentoxifylline (PTX) may be useful in the treatment of sepsis. We examined effects of PTX in a conscious swine model of sepsis. Yucatan minipigs (20-30 kg) were anesthetized and instrumented with catheters in the vena ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::776f06ff6205a72be85bc8a8bf18a838
https://pubmed.ncbi.nlm.nih.gov/1446387

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Pathological evaluation of WR-151327 administered orally in irradiated and non-irradiated male mice

Autor: L, Steel-Goodwin, J M, Kendrick, J E, Egan, J M, Eckstein

Publikováno v: Annals of clinical and laboratory science. 22(3)

Studies were made on the radioprotective and toxic effects of orally administered WR-151327 in male CD2F1 mice. The lowest dose of orally administered drug permitting probit analysis of data was 450 mg per kg. The calculated radioprotective dose redu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::03384cb85e54834a3a0f386c91b4cdda
https://pubmed.ncbi.nlm.nih.gov/1503385

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