Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J M, Chirgwin"'
Autor:
J M, Chirgwin, T A, Guise
Publikováno v:
Journal of musculoskeletalneuronal interactions. 3(4)
Publikováno v:
Journal of musculoskeletalneuronal interactions. 4(3)
Human tumor cells inoculated into the arterial circulation of immunocompromised mice can reliably cause bone metastases, reproducing many of the clinical features seen in patients. Animal models permit the identification of tumor-produced factors, wh
Autor:
J M, Chirgwin, T A, Guise
Publikováno v:
Critical reviews in eukaryotic gene expression. 10(2)
In patients with advanced disease, several cancer types frequently metastasize to the skeleton, where they cause bone destruction. Osteolytic metastases are incurable and cause pain, hypercalcemia, fracture, and nerve compression syndromes. It was pr
Autor:
D, Sachdev, J M, Chirgwin
Publikováno v:
Methods in enzymology. 326
Publikováno v:
Advances in experimental medicine and biology. 436
Publikováno v:
Advances in experimental medicine and biology. 436
Publikováno v:
Calcified tissue international. 62(4)
Corynebacterium matruchotii is a microbial inhabitant of the oral cavity associated with dental calculus formation. It produces membrane-associated proteolipid capable of inducing hydroxyapatite formation in vitro. This proteolipid was purified from
Publikováno v:
The Journal of biological chemistry. 269(46)
Autocrine products of osteoclasts such as interleukin-6 may play an important role in normal osteoclast formation and activity. To identify novel stimulatory factors for osteoclasts, we have prepared a mammalian cDNA expression library generated from
Publikováno v:
The Journal of biological chemistry. 269(44)
Rhodanese is a small (33 kDa) monomeric sulfurtransferase which is synthesized on cytoplasmic ribosomes and imported into the mitochondrial matrix without cleavage of its amino terminus. When we transfected mammalian cell lines with rhodanese cDNA un
Publikováno v:
The Journal of biological chemistry. 269(5)
Mutants of rhodanese (EC 2.8.1.1) which substitute serine residues for each of the 4 cysteine residues have been studied to determine the roles of cysteines in the structure and function of the enzyme. The proteins compared in these studies were: the