Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J M, Carboni"'
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(12)
Taxol, a potent antitumor agent that binds beta-tubulin and promotes microtubule assembly, results in mitotic arrest at the G2/M phase of the cell cycle. More recently, Taxol was shown to be a potent LPS mimetic in murine, but not in human macrophage
Autor:
B H, Long, J M, Carboni, A J, Wasserman, L A, Cornell, A M, Casazza, P R, Jensen, T, Lindel, W, Fenical, C R, Fairchild
Publikováno v:
Cancer research. 58(6)
Eleutherobin is a novel natural product isolated from a marine soft coral that is extremely potent for inducing tubulin polymerization in vitro and is cytotoxic for cancer cells with an IC50 similar to that of paclitaxel. This compound is cross-resis
Autor:
J M, Carboni, N, Yan, A D, Cox, X, Bustelo, S M, Graham, M J, Lynch, R, Weinmann, B R, Seizinger, C J, Der, M, Barbacid
Publikováno v:
Oncogene. 10(10)
Recent results from several laboratories including ours strongly suggest that farnesyltransferase (FT) inhibitors belonging to distinct chemical classes block growth of oncogenic Ras transformed cells at concentrations that do not affect the growth a
Publikováno v:
ACS Symposium Series ISBN: 9780841230736
Taxane Anticancer Agents: Basic Science and Current Status
Taxane Anticancer Agents: Basic Science and Current Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::821b2e0f725f161c4493d930a17626ea
https://doi.org/10.1021/bk-1995-0583.ch012
https://doi.org/10.1021/bk-1995-0583.ch012
Autor:
M J, Lynch, L, Pelosi, J M, Carboni, J, Merwin, K, Coleman, R C, Wang, P F, Lin, D L, Henry, M G, Brattain
Publikováno v:
Cancer research. 53(17)
FET cells are well differentiated human adenocarcinoma cells whose growth is partially inhibited (50-60%) by transforming growth factor-beta 1 (TGF-beta 1). In exponentially growing cultures, TGF-beta 1 induces the expression of transforming growth f
Publikováno v:
Journal of the National Cancer Institute. Monographs. (15)
Taxol, a unique antimitotic drug, is thought to exert its antitumor activity by binding to and promoting the assembly of microtubules. Studies on the mechanism of action of Taxol have focused mainly on this ability to induce microtubule polymerizatio
Publikováno v:
The Journal of Cell Biology
The actin bundle within each microvillus of the intestinal brush border is tethered laterally to the membrane by spirally arranged bridges. These bridges are thought to be composed of a protein complex consisting of a 110-kD subunit and multiple mole
Publikováno v:
The Journal of Cell Biology
The assembly of the intestinal microvillus cytoskeleton during embryogenesis in the chick was examined by immunochemical and light microscopic immunolocalization techniques. For these studies, affinity-purified antibodies reactive with three major cy
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 115(5)
Complement receptor lymphocytes were demonstrated in rabbit lymphoid organs, the spleen containing the highest numbers (35%) and the thymus none. Extremely variable numbers (up to 50%) were detectablein the appendix. B and T cell depletion, rosette d
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 121(3)