Výsledky vyhledávání - "J M, Carballido"

Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule

Autor: J M Carballido, G Aversa, K Kaltoft, B G Cocks, J Punnonen, H Yssel, K Thestrup-Pedersen, J E de Vries

Publikováno v: The Journal of Immunology. 159:4316-4321

Allergen-specific Th2 cells accumulate at high frequencies in the skin of patients with atopic dermatitis (AD), where they contribute to the induction and maintenance of the lesions that are characteristic for the disease. Attenuation of these lesion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::727c60a74b455de16e9b708b4e57d191
https://doi.org/10.4049/jimmunol.159.9.4316

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Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production

Autor: G Aversa, C C Chang, J M Carballido, B G Cocks, J E de Vries

Publikováno v: The Journal of Immunology. 158:4036-4044

The expression and function of the novel signaling lymphocytic activation molecule (SLAM) are described. SLAM is present on immature thymocytes, CD45R0(high) memory T cells, T cell clones, CD56+ T cells, EBV-transformed B-cell lines and on a proporti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27d8e1fcc441e7afc18cd884a6e274e0
https://doi.org/10.4049/jimmunol.158.9.4036

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Selective restimulation of antigen or allergen preactivated T cells using OKT3 F(ab)2 results in the secretion of TH-1 or TH-2-like cytokine patterns

Autor: J. M. Carballido, Kurt Blaser, Tony Wyss-Coray, Marek Jutel, Ulrich R. Müller, Werner J. Pichler

Publikováno v: Clinical & Experimental Allergy. 25:1108-1117

Summary Background The synthesis of IgE is regulated by cytokines secreted from T-helper cells. The studies on cytokine secretion by peripheral blood mononuclear cells (PBMC) upon stimulation with antigen or allergen are ditficult due to low levels o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ad0013487ff74a65c9bcdf542d553e
https://doi.org/10.1111/j.1365-2222.1995.tb03258.x

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IL-10 transgenic mice present a defect in T cell development reminiscent of SCID patients

Autor: M, Rouleau, F, Cottrez, M, Bigler, S, Antonenko, J M, Carballido, A, Zlotnik, M G, Roncarolo, H, Groux

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(3)

To analyze the effect of IL-10 overexpressed by APCs as observed in some SCID patients, we have expressed the human IL-10 cDNA under the control of the murine MHC class II promoter in transgenic mice. Similar to SCID patients, these mice presented a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::47921a3194902c9ddcd2827b9276e17a
https://pubmed.ncbi.nlm.nih.gov/10415042

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Reversal of human allergic T helper 2 responses by engagement of signaling lymphocytic activation molecule

Autor: J M, Carballido, G, Aversa, K, Kaltoft, B G, Cocks, J, Punnonen, H, Yssel, K, Thestrup-Pedersen, J E, de Vries

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2285518d104757aec4111074f304e9b
https://pubmed.ncbi.nlm.nih.gov/9379027

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Engagement of the signaling lymphocytic activation molecule (SLAM) on activated T cells results in IL-2-independent, cyclosporin A-sensitive T cell proliferation and IFN-gamma production

Autor: G, Aversa, C C, Chang, J M, Carballido, B G, Cocks, J E, de Vries

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 158(9)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d5c2f8a23959306dc5bbfb97a8244cb
https://pubmed.ncbi.nlm.nih.gov/9126961

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IL-4 induces human B cell maturation and IgE synthesis in SCID-hu mice. Inhibition of ongoing IgE production by in vivo treatment with an IL-4/IL-13 receptor antagonist

Autor: J M, Carballido, D, Schols, R, Namikawa, S, Zurawski, G, Zurawski, M G, Roncarolo, J E, de Vries

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 155(9)

The effect of cytokine treatment on the in vivo maturation and Ig isotype switching of human B cells was studied in a modified SCID-hu mouse model. SCID mice, subcutaneously cotransplanted with small fragments of fetal human thymus and bone (SCID-hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d04a266c855ea2795b63882deae09a8
https://pubmed.ncbi.nlm.nih.gov/7594571

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Regulation of IgE and IgG4 responses by allergen specific T-cell clones to bee venom phospholipase A2 in vitro

Autor: J M, Carballido, N, Carballido-Perrig, A, Oberli-Schrämmli, C H, Heusser, K, Blaser

Publikováno v: The Journal of allergy and clinical immunology. 93(4)

An in vitro antibody response to bee venom phospholipase A2 (PLA) from peripheral blood mononuclear cells of bee sting-sensitized individuals was achieved after stimulation with PLA and pokeweed mitogen. This stimulation resulted in a secretion of TH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b0703d021687b9bf640ec5958b0b153
https://pubmed.ncbi.nlm.nih.gov/8163785

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