Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J M, Bartlett"'
Autor:
J R, Reeves, J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
In common with other tumor types, ovarian cancer is a genetic disease and work at the DNA or RNA level is crucial to gain an understanding of the genetic changes leading to tumor formation. Phenotypic change, however, is the result of loss or aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a62c5fd7f25a37c867e26d5ea1b28534
https://pubmed.ncbi.nlm.nih.gov/21340803
https://pubmed.ncbi.nlm.nih.gov/21340803
Autor:
J, Edwards, J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
The epidermal growth factor receptor (EGFr) is a 170-kDa glycosylated transmembrane protein found in a wide variety of tissues (1). It is the receptor for epidermal growth factor (EGF), transforming growth factor α (TGFα), and other related growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12079d2df16aebe7095dd9bdccae3245
https://pubmed.ncbi.nlm.nih.gov/21340815
https://pubmed.ncbi.nlm.nih.gov/21340815
Autor:
J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
RNase protection assays provide a level of sensitivity some 20-50-fold greater than Northern blots, and can be used to accurately identify and quantify different mRNA species within gene families even when a high degree of sequence homology exists. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e202e44df3ffe0a0225764c485eea4bb
https://pubmed.ncbi.nlm.nih.gov/21340799
https://pubmed.ncbi.nlm.nih.gov/21340799
Publikováno v:
Methods in molecular medicine. 39
Perhaps the most fundamental question that faces the laboratory scientist is, "Which model system should I use to investigate the problem?" Failure to adequately address this issue can compromise even the most meticulous and inspired research program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c4108d7f5c7571f0be2e70323d97d92
https://pubmed.ncbi.nlm.nih.gov/21340765
https://pubmed.ncbi.nlm.nih.gov/21340765
Autor:
J, Edwards, J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
An important convergence point involved in the signal transduction pathways of many different growth factors, hormones, and cytokines are the p42 and p44 serine/ threonine kinases called either MAP kinases (mitogen-activate protein kinases) or ERK 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb285e3d71c9ccc9da596888c9509a5f
https://pubmed.ncbi.nlm.nih.gov/21340816
https://pubmed.ncbi.nlm.nih.gov/21340816
Autor:
J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
This section deals with techniques of mRNA analysis, both qualitative and quantitative. The technical details for the techniques described in this section are included in the chapters themselves. In this overview, some of the fundamentals that resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c469fef81ad9d04aeee803d1413fd732
https://pubmed.ncbi.nlm.nih.gov/21340796
https://pubmed.ncbi.nlm.nih.gov/21340796
Autor:
A D, Watters, J M, Bartlett
Publikováno v:
Methods in molecular medicine. 39
The term interphase cytogenetics was first used in 1986 by Cremer (1,2) to describe detection of chromosomal alterations using in situ techniques in interphase nuclei. This was a distinct advantage over conventional analyses as solid tumors could now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50c1ef64cc084ab3772d45a1954e1240
https://pubmed.ncbi.nlm.nih.gov/21340780
https://pubmed.ncbi.nlm.nih.gov/21340780
Publikováno v:
BJU international. 88(6)
To examine the role of androgen receptor (AR) gene amplification and aneusomy of the X chromosome in the development of antiandrogen-resistant prostate cancer.Twenty patients with prostate cancer resistant to androgen-deprivation therapy were selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e77f7183a9117aafecdd577fc702edb
https://pubmed.ncbi.nlm.nih.gov/11678763
https://pubmed.ncbi.nlm.nih.gov/11678763
Publikováno v:
Urologia internationalis. 67(3)
N-acetyltransferase 2 (NAT2), mapped to 8p22, is a polymorphic enzyme which metabolizes aromatic amines. Loss of heterozygosity of 8p22 is associated with an increased risk of bladder cancer. This study evaluated NAT2 and chromosome 8 in sequential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b9613b0ed7511a6cbd15dbbb03f8fc4
https://pubmed.ncbi.nlm.nih.gov/11598453
https://pubmed.ncbi.nlm.nih.gov/11598453
Publikováno v:
BJU international. 84(7)
To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dabefcfa0cc51e8521943f1c7c75f14e
https://pubmed.ncbi.nlm.nih.gov/10532970
https://pubmed.ncbi.nlm.nih.gov/10532970