Zobrazeno 1 - 10
of 19
pro vyhledávání: '"J M, Agosti"'
Autor:
Raul A. DeLa Cadena, J M Agosti, Antoni Stadnicki, Abraham Majluf-Cruz, Robert W. Colman, Anthony F. Suffredini
Publikováno v:
Immunopharmacology. 33:231-237
Severe progressive failure of multiple organ systems has emerged during the past three decades as a common cause of death among patients in intensive care units. Sepsis is now better defined as systemic inflammatory response syndrome (SIRS), but its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c232d23ff11111d50291b1c302e70952
https://doi.org/10.1016/0162-3109(96)00064-1
https://doi.org/10.1016/0162-3109(96)00064-1
Publikováno v:
The Journal of Immunology. 155:5038-5045
Effects of dimeric TNF receptor (p80) Fc (TNFR:Fc) on acute phase responses were evaluated in 18 volunteers given endotoxin (4 ng/kg i.v.). Subjects were randomized to receive either placebo (n = 6), low dose TNFR:Fc (10 mg/m2 i.v., n = 6), or high d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baff39a2d189f313b96eaae99b53d332
https://doi.org/10.4049/jimmunol.155.10.5038
https://doi.org/10.4049/jimmunol.155.10.5038
Autor:
R J, Looney, M S, Hasan, D, Coffin, D, Campbell, A R, Falsey, J, Kolassa, J M, Agosti, G N, Abraham, T G, Evans
Publikováno v:
Journal of clinical immunology. 21(1)
The efficacy of granulocyte-macrophage colony-stimulating factor (GM-CSF) to enhance the primary immune response to hepatitis B vaccine was studied in healthy elderly with young volunteers included as controls in this double-blind, placebo-controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0df48d20ceb2659439d09942c2fca57
https://pubmed.ncbi.nlm.nih.gov/11321236
https://pubmed.ncbi.nlm.nih.gov/11321236
Autor:
J B, Angel, K, High, F, Rhame, D, Brand, J B, Whitmore, J M, Agosti, M J, Gilbert, S, Deresinski
Publikováno v:
AIDS (London, England). 14(4)
To evaluate the effect of adjuvant granulocyte-macrophage colony-stimulating factor (GM-CSF) (sargramostim, yeast-derived recombinant human GM-CSF) on incidence and time to opportunistic infection or death, plasma HIV-RNA, and CD4 cell count in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcf9ed2b8a06c637fddd78abe23fb910
https://pubmed.ncbi.nlm.nih.gov/10770541
https://pubmed.ncbi.nlm.nih.gov/10770541
Publikováno v:
American journal of physiology, 276(2 Part 2), R357-R362. American Physiological Society
To determine the role of tumor necrosis factor (TNF) in endotoxin-induced changes in plasma thyroid hormone and thyroid-stimulating hormone (TSH) concentrations, 24 healthy postabsorptive humans were studied on a control study day ( n= 6), after infu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024fc2025e83eece0fb2942ac8f8dc48
https://pubmed.ncbi.nlm.nih.gov/9950912
https://pubmed.ncbi.nlm.nih.gov/9950912
Autor:
R A, DeLa Cadena, A, Majluf-Cruz, A, Stadnicki, M, Tropea, D, Reda, J M, Agosti, R W, Colman, A F, Suffredini
Publikováno v:
Thrombosis and haemostasis. 80(1)
The effects of inhibition of tumor necrosis factor (TNF) on cell and protease activation were evaluated in 18 normal volunteers given endotoxin (4 ng/kg, i.v.) after an infusion of low (10 mg/m2 i.v., n = 6) or high dose (60 mg/m2 i.v., n = 6) recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00d4e7d73a04f66be694f3d6bf6a8eb4
https://pubmed.ncbi.nlm.nih.gov/9684796
https://pubmed.ncbi.nlm.nih.gov/9684796
Autor:
T, van der Poll, S M, Coyle, M, Levi, P M, Jansen, M, Dentener, K, Barbosa, W A, Buurman, C E, Hack, J W, ten Cate, J M, Agosti, S F, Lowry
Publikováno v:
Blood. 89(10)
To determine the role of tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-induced inflammation, 12 healthy subjects received an intravenous injection with LPS (2 ng/kg) preceded by infusion of either a recombinant human dimeric TNF receptor ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0957419fef8939b8184454404b0ee401
https://pubmed.ncbi.nlm.nih.gov/9160678
https://pubmed.ncbi.nlm.nih.gov/9160678
Publikováno v:
Blood. 88(7)
Effects of soluble recombinant human type I interleukin-1 receptor (sIL-1RI) were evaluated in 18 volunteers given intravenous endotoxin and randomized to placebo (n = 6), low-dose (n = 6), or high-dose (n = 6) sIL-1RI. Soluble IL-1RI decreased IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5740b69021b938fad87ed1f975b6a77
https://pubmed.ncbi.nlm.nih.gov/8839837
https://pubmed.ncbi.nlm.nih.gov/8839837
Autor:
C J, Fisher, J M, Agosti, S M, Opal, S F, Lowry, R A, Balk, J C, Sadoff, E, Abraham, R M, Schein, E, Benjamin
Publikováno v:
The New England journal of medicine. 334(26)
A recombinant, soluble fusion protein that is a dimer of an extracellular portion of the human tumor necrosis factor (TNF) receptor and the Fc portion of IgG1 (TNFR:Fc) binds and neutralizes TNF-alpha and prevents death in animal models of bacteremia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be0d27b27a85d9e0fb9d2a7acf90ad12
https://pubmed.ncbi.nlm.nih.gov/8927112
https://pubmed.ncbi.nlm.nih.gov/8927112
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(10)
Effects of dimeric TNF receptor (p80) Fc (TNFR:Fc) on acute phase responses were evaluated in 18 volunteers given endotoxin (4 ng/kg i.v.). Subjects were randomized to receive either placebo (n = 6), low dose TNFR:Fc (10 mg/m2 i.v., n = 6), or high d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62b19acabadee77a75dd2f8830b53c43
https://pubmed.ncbi.nlm.nih.gov/7594512
https://pubmed.ncbi.nlm.nih.gov/7594512