Výsledky vyhledávání - "J M, Ackermann"

The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes

Autor: N, Chauret, B, Dobbs, R L, Lackman, K, Bateman, D A, Nicoll-Griffith, D M, Stresser, J M, Ackermann, S D, Turner, V P, Miller, C L, Crespi

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 29(9)

Recently, a novel nonfluorescent probe 3-[2-(N,N-diethyl-N-methylammonium)-ethyl]-7-methoxy-4-methylcoumarin (AMMC), which produces a fluorescent metabolite AMHC (3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-hydroxy-4-methylcoumarin) was used with mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::774704df99b987261dcdbadd6bd67104
https://pubmed.ncbi.nlm.nih.gov/11502727

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Effect of methanol, ethanol, dimethyl sulfoxide, and acetonitrile on in vitro activities of cDNA-expressed human cytochromes P-450

Autor: W F, Busby, J M, Ackermann, C L, Crespi

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 27(2)

The effects of methanol, ethanol, dimethyl sulfoxide (DMSO), and acetonitrile were studied in vitro on nine individual, cDNAexpressed cytochrome P-450 activities (phenacetin O-deethylase for CYP1A1 and CYP1A2, coumarin 7-hydroxylase for CYP2A6, testo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9343496f924c3194778690dafb7ad3c
https://pubmed.ncbi.nlm.nih.gov/9929510

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