Zobrazeno 1 - 10
of 387
pro vyhledávání: '"J Licht"'
Autor:
Gerard H. Laurent, ScB, Tiffany S. Ko, PhD, Kobina G. Mensah-Brown, MD, MS, Constantine D. Mavroudis, MD, MSC, MTR, Marin Jacobwitz, CRNP, PhD, Nicolina Ranieri, BSc, Susan C. Nicolson, MD, J. William Gaynor, MD, Wesley B. Baker, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Jennifer M. Lynch, MD, PhD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 801-809 (2023)
Objectives: Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter injury. The objective of this study is to
Externí odkaz:
https://doaj.org/article/4c29f008c2cf4b1d92d84d6f9cd52cfe
Autor:
Jill Hsia, MD, Nicholas S. Abend, MD, MSCE, J. William Gaynor, MD, Jonathan M. Chen, MD, Stephanie Fuller, MD, Katsuhide Maeda, MD, PhD, Constantine D. Mavroudis, MD, MSc, MTR, Muhammad Nuri, MD, Jan Leonard, MSPH, Steve B. Ampah, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Maryam Y. Naim, MD, MSCE
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 771-783 (2023)
Objectives: Historically, our center has primarily used deep hypothermic circulatory arrest, but in recent years some surgeons have selectively used regional cerebral perfusion as an alternative. We aimed to compare the incidence of postoperative ele
Externí odkaz:
https://doaj.org/article/a3dd7e7965cd4bc48730f96c09dd7975
Autor:
Giselle C Matlis, Qihuang Zhang, Emilie J Benson, M Katie Weeks, Kristen Andersen, Jharna Jahnavi, Alec Lafontant, Jake Breimann, Thomas Hallowell, Yuxi Lin, Daniel J Licht, Arjun G Yodh, Todd J Kilbaugh, Rodrigo M Forti, Brian R White, Wesley B Baker, Rui Xiao, Tiffany S Ko
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305254 (2024)
Advanced optical neuromonitoring of cerebral hemodynamics with hybrid diffuse optical spectroscopy (DOS) and diffuse correlation spectroscopy (DCS) methods holds promise for non-invasive characterization of brain health in critically ill patients. Ho
Externí odkaz:
https://doaj.org/article/7eb3bbb0e763410fb1775119e59a3caa
Autor:
Kalil Shaw, Constantine D. Mavroudis, Tiffany S. Ko, Jharna Jahnavi, Marin Jacobwitz, Nicolina Ranieri, Rodrigo M. Forti, Richard W. Melchior, Wesley B. Baker, Arjun G. Yodh, Daniel J. Licht, Susan C. Nicolson, Jennifer M. Lynch
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundSurgical procedures involving the aortic arch present unique challenges to maintaining cerebral perfusion, and optimal neuroprotective strategies to prevent neurological injury during such high-risk procedures are not completely understood.
Externí odkaz:
https://doaj.org/article/94e67cbe43c04745bdfe1432f4e5c1ef
Autor:
James K. Moon, MD, Kendall M. Lawrence, MD, Mallory L. Hunt, MD, MBE, Marcus G. Davey, PhD, Alan W. Flake, MD, Daniel J. Licht, MD, Jonathan M. Chen, MD, Todd J. Kilbaugh, MD, J. William Gaynor, MD, Daniel P. Beiting, PhD
Publikováno v:
JTCVS Open, Vol 10, Iss , Pp 342-349 (2022)
Objective: The molecular pathways underlying hypoxemia-induced alterations in neurodevelopment of infants with congenital heart disease have not been delineated. We used transcriptome analysis to investigate differential gene expression induced by hy
Externí odkaz:
https://doaj.org/article/b4695444847e46a0ad8e73509db2acf1
Autor:
Daniel J. Licht, Marin Jacobwitz, Jennifer M. Lynch, Tiffany Ko, Timothy Boorady, Mahima Devarajan, Kristina N. Heye, Kobina Mensah‐Brown, John J. Newland, Alexander Schmidt, Peter Schwab, Madeline Winters, Susan C. Nicolson, Lisa M. Montenegro, Stephanie Fuller, Christopher Mascio, J. William Gaynor, Arjun G. Yodh, Juliana Gebb, Arastoo Vossough, Grace H. Choi, Mary E. Putt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 7 (2023)
Background Infants with congenital heart disease (CHD) are at risk for white matter injury (WMI) before neonatal heart surgery. Better knowledge of the causes of preoperative WMI may provide insights into interventions that improve neurodevelopmental
Externí odkaz:
https://doaj.org/article/5e8f59e94cbe40f285e4476f2afa76db
Autor:
Emilie J. Benson, Danielle I. Aronowitz, Rodrigo M. Forti, Alec Lafontant, Nicolina R. Ranieri, Jonathan P. Starr, Richard W. Melchior, Alistair Lewis, Jharna Jahnavi, Jake Breimann, Bohyun Yun, Gerard H. Laurent, Jennifer M. Lynch, Brian R. White, J. William Gaynor, Daniel J. Licht, Arjun G. Yodh, Todd J. Kilbaugh, Constantine D. Mavroudis, Wesley B. Baker, Tiffany S. Ko
Publikováno v:
Metabolites, Vol 13, Iss 11, p 1153 (2023)
Cardiopulmonary bypass (CPB) provides cerebral oxygenation and blood flow (CBF) during neonatal congenital heart surgery, but the impacts of CPB on brain oxygen supply and metabolic demands are generally unknown. To elucidate this physiology, we used
Externí odkaz:
https://doaj.org/article/412899bb1f7d4941a34146ce6a1c8ab8
Autor:
Benjamin Meyers, Vincent K. Lee, Lauren Dennis, Julia Wallace, Vanessa Schmithorst, Jodie K. Votava-Smith, Vidya Rajagopalan, Elizabeth Herrup, Tracy Baust, Nhu N. Tran, Jill V. Hunter, Daniel J. Licht, J. William Gaynor, Dean B. Andropoulos, Ashok Panigrahy, Rafael Ceschin
Publikováno v:
Neuroimage: Reports, Vol 2, Iss 3, Pp 100114- (2022)
Advanced brain imaging of neonatal macrostructure and microstructure, which has prognosticating importance, is more frequently being incorporated into multi-center trials of neonatal neuroprotection. Multicenter neuroimaging studies, designed to over
Externí odkaz:
https://doaj.org/article/06ba43d0f35a454cbc33689a8ab8dd29
Autor:
Tiffany S. Ko, Constantine D. Mavroudis, Ryan W. Morgan, Wesley B. Baker, Alexandra M. Marquez, Timothy W. Boorady, Mahima Devarajan, Yuxi Lin, Anna L. Roberts, William P. Landis, Kobina Mensah-Brown, Vinay M. Nadkarni, Robert A. Berg, Robert M. Sutton, Arjun G. Yodh, Daniel J. Licht, Wensheng Guo, Todd J. Kilbaugh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Neurologic injury is a leading cause of morbidity and mortality following pediatric cardiac arrest. In this study, we assess the feasibility of quantitative, non-invasive, frequency-domain diffuse optical spectroscopy (FD-DOS) neuromonitorin
Externí odkaz:
https://doaj.org/article/357b300a7e434438a8ef0a890b5f4cb3
Autor:
Constantine D. Mavroudis, Tiffany S. Ko, Ryan W. Morgan, Lindsay E. Volk, William P. Landis, Benjamin Smood, Rui Xiao, Marco Hefti, Timothy W. Boorady, Alexandra Marquez, Michael Karlsson, Daniel J. Licht, Vinay M. Nadkarni, Robert A. Berg, Robert M. Sutton, Todd J. Kilbaugh
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-13 (2020)
Abstract Background Despite controversies, epinephrine remains a mainstay of cardiopulmonary resuscitation (CPR). Recent animal studies have suggested that epinephrine may decrease cerebral blood flow (CBF) and cerebral oxygenation, possibly potentia
Externí odkaz:
https://doaj.org/article/73429063db8242768066239a18d24bff