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pro vyhledávání: '"J Lee Franklin"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 211-216 (2017)
Proinflammatory cytokines, including TNF-α and IL-6, can contribute to insulin resistance. Conversely, insulin has some actions that can be considered anti-inflammatory. Hemopexin is a Class 2 acute phase reactant and control of its transcription is
Externí odkaz:
https://doaj.org/article/6d129da18a844fe5b4e79940493587af
Publikováno v:
Cell Stress Chaperones
While screening for insulin-induced genes, we identified two members of a family of stress-induced genes referred to as glucose-regulated proteins (GRPs). GRPs are members of the stress-responsive superfamily of genes which also includes heat shock p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b87361864d923313130eba0943825f1
https://europepmc.org/articles/PMC8821767/
https://europepmc.org/articles/PMC8821767/
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 211-216 (2017)
Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 211-216 (2017)
Proinflammatory cytokines, including TNF-α and IL-6, can contribute to insulin resistance. Conversely, insulin has some actions that can be considered anti-inflammatory. Hemopexin is a Class 2 acute phase reactant and control of its transcription is
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1863(10 Pt)
Insulin resistance and metabolic dysfunction are common following injury. Polytrauma is defined as combined injuries to more than one body part or organ system, and is common in modern warfare, as well as automobile and industrial accidents. Polytrau
Increased activity of prenyl transferases is observed in pathological states of insulin resistance, diabetes, and obesity. Thus, functional inhibitors of farnesyl transferase (FTase) and geranylgeranyl transferase (GGTase) may be promising therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5351b0b8d5b7032a520f316890ad1228
https://europepmc.org/articles/PMC5373655/
https://europepmc.org/articles/PMC5373655/
Publikováno v:
Hepatic Medicine : Evidence and Research
Katherine D Bortoff1, Adam B Keeton1, J Lee Franklin1, Joseph L Messina1,21Department of Pathology, Division of Molecular and Cellular Pathology, The University of Alabama at Birmingham, Birmingham, Alabama, USA; 2Veterans Affairs Medical Center, Bir
Publikováno v:
International journal of clinical and experimental medicine. 1(1)
Insulin regulates metabolism and growth in cells of hepatic origin by specifically binding to and activating the tyrosine kinase insulin receptor. Insulin-induced intracellular signaling is conducted via multiple pathways, including the MAP kinase (M
Publikováno v:
Endocrinology. 146(6)
In the present work, insulin’s regulation of expression of activating transcription factor 3 (ATF-3), the putative transcription factor proline-rich induced protein (Pip)92, and insulin-inducible gene-1 (Insig-1) (an ER resident protein involved in
Publikováno v:
Biochimica et biophysica acta. 1679(3)
Gene33 and its human homologue, mitogen inducible gene-6/receptor-associated late transducer (mig-6, RALT), is a 53-kDa soluble protein that was identified as a hepatic gene regulated by glucocorticoids and insulin. Its mRNA is expressed in numerous
Publikováno v:
Shock. 21:20