Výsledky vyhledávání

Subjective Complaints as the Main Reason for Biosimilar Discontinuation After Open-Label Transition From Reference Infliximab to Biosimilar Infliximab

Autor: Alfons A den Broeder, Frank H J van den Hoogen, Iris L A van Ingen, Alphons J L de Jong, L. Tweehuysen, Willemijn H. van der Laan, Bart J F van den Bemt

Publikováno v: Arthritis & Rheumatology, 70, 60-68
Arthritis & Rheumatology, 70, 1, pp. 60-68

Objective To evaluate drug survival, effectiveness, pharmacokinetics, immunogenicity, and safety in daily practice after transitioning treatment from original reference infliximab (Remicade [REM]) to a biosimilar infliximab (CT-P13 [Remsima; Inflectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860b85c717b9bb8818db32a1977b3d62
https://doi.org/10.1002/art.40324

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The patient perspective on biologic DMARD dose reduction in rheumatoid arthritis: a mixed methods study

Autor: Johanna E. Vriezekolk, E.M. Selten, Lise M Verhoef, Alfons A den Broeder, Marlies E J L Hulscher, Alphons J L de Jong, Frank H J van den Hoogen

Publikováno v: Rheumatology, 57, 1947-1955
Rheumatology, 57, 11, pp. 1947-1955

Objectives The aim of this study was to identify the factors that play a role for patients with RA when considering dose reduction (i.e. gradual tapering until discontinuation) of biological DMARDs (bDMARDs), and to determine their relative importanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d063f44b86c10840cd93188c3073666b
https://doi.org/10.1093/rheumatology/key205

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A clinical and serological comparison of group A versus non-group A streptococcal reactive arthritis and throat culture negative cases of post-streptococcal reactive arthritis

Autor: R. Traksel, T.L.Th.A. Jansen, Matthijs Janssen, A. J. L. De Jong

Publikováno v: Annals of the Rheumatic Diseases. 58:410-414

OBJECTIVE—To identify clinical and serological differences of patients with reactive arthritis after infection with Lancefield group A β-haemolytic streptococci (GAS), compared with non-group A—that is, group C or G streptococci (NGAS:GCS/GGS),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1c882f48f81c2e7b046caec561cdde
https://doi.org/10.1136/ard.58.7.410

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Interaction of IL-15 with the shared IL-2 receptor beta and gamma c subunits. The IL-15/beta/gamma c receptor-ligand complex is less stable than the IL-2/beta/gamma c receptor-ligand complex

Autor: J L de Jong, N L Farner, M B Widmer, J G Giri, P M Sondel

Publikováno v: The Journal of Immunology. 156:1339-1348

This study was designed to compare the interactions of IL-2 and IL-15 with the IL-2R beta and IL-2R gamma c subunits, as differences in receptor interactions between IL-2 and IL-15 might contribute to the functional differences between these two cyto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18aacac3b78a7909c03259696834aefc
https://doi.org/10.4049/jimmunol.156.4.1339

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Sequential quadratic programming methods for optimal control problems with state constraints

Autor: J. L. de Jong, Xu Chengxian

Publikováno v: Applied Mathematics-A Journal of Chinese Universities. 8:163-174

A kind of direct methods is presented for the solution of optimal control problems with state constraints. These methods are sequential quadratic programming methods. At every iteration a quadratic programming which is obtained by quadratic approxima

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1af0944e0acf24470a66197b405d3c32
https://doi.org/10.1007/bf02662000

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