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Akademický článek
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Publikováno v:
Endocrinology. 137:2059-2066
Studies were conducted to evaluate the susceptibility of avian ovarian granulosa cells to apoptosis when incubated in vitro and to relate this relative susceptibility to both the stage of follicle development from which granulosa cells were collected
Autor:
J. L Tilly
Publikováno v:
Frontiers in Bioscience. 1:d1-11
Physiological cell death mechanisms (termed apoptosis, programmed cell death, active cell death, and biological cell death) play a fundamental role in the cyclic function of the ovary as it strives in each cycle to ovulate a viable egg for fertilizat
Realizing the promise of apoptosis-based therapies: separating the living from the clinically undead
Autor:
J L Tilly, R N Kolesnick
Publikováno v:
Cell Death & Differentiation. 10:493-495
Realizing the promise of apoptosis-based therapies: separating the living from the clinically undead
Publikováno v:
Cell Death and Differentiation. 9:96-98
Publikováno v:
British Journal of Cancer
In this study we have investigated the interaction of caffeine, a prototypic methylxanthine, and TNF on the induction of cell death in mouse and human cell lines during progression from G1 to successive phases of the cell cycle. Exposure of cells to
Autor:
J. L. Tilly
Publikováno v:
Endocrinology. 130:1296-1302
Publikováno v:
Biology of Reproduction. 46:195-200
The hormonal and second messenger regulation of plasminogen activator (PA) activities in avian granulosa and theca cells has been documented. However, the physiological role(s) of PAs in the avian ovary remains poorly understood. The present studies
Publikováno v:
Biology of Reproduction. 45:967-974
Previous studies have indicated that developing avian granulosa cells collected from follicles 2-3 wk prior to ovulation (e.g. 6-8-mm in diameter) are steroidogenically incompetent, apparently due to a lack of functional cytochrome P450 side-chain cl