Zobrazeno 1 - 10
of 217
pro vyhledávání: '"J L Spivak"'
Autor:
A. G. Smith
Publikováno v:
Hematological Oncology. 5:232-232
Autor:
J L Spivak
Publikováno v:
Leukemia Supplements. 3:S23-S24
Polycythemia vera (PV) is the most common chronic myeloproliferative disorder (MPD), having an incidence of 2.5 per 100 000 MPD cases. PV is a clonal stem cell disease causing the unregulated production of morphologically normal red cells, white cell
Autor:
J L, Spivak
Publikováno v:
Annual Review of Medicine. 44:243-253
Erythropoietin is the only hematopoietic growth factor that behaves like a hormone. Produced in the kidneys and the liver, erythropoietin interacts with erythroid progenitor cells in the bone marrow to promote their proliferation and maintain their v
Publikováno v:
Blood. 80:2677-2682
Delayed erythroid recovery is common after bone marrow transplantation (BMT), with some patients continuing to require red blood cell (RBC) transfusion support for as long as 1 year. While the etiology is multifactorial, inadequate stimulation of ery
Autor:
J L, Spivak
Publikováno v:
Advances in experimental medicine and biology. 502
The major function of the erythrocyte is to transport oxygen from the lungs to the other tissues, a function ensured by the glycoprotein hormone erythropoietin which couples red cell production to long term tissue oxygen requirements. Tissue hypoxia
Publikováno v:
Journal of clinical epidemiology. 54(4)
Mailed surveys are a popular means of obtaining data on large populations. In July 1999 a mail survey was conducted among 3000 randomly selected members of the American Society of Hematology to assess their approach to diagnosis and treatment of poly
Autor:
J L, Spivak, M, Cazzola
Publikováno v:
Medical oncology (Northwood, London, England). 17
At the recent EHA meeting in Birmingham, UK, an expert audience of haematologists and oncologists were polled using keypad technology on current thinking and treatment practices in anaemia in cancer patients. More than 76% of the audience thought tha
Autor:
A R, Moliterno, J L, Spivak
Publikováno v:
Blood. 94(8)
Recently, we demonstrated a marked reduction in the expression of the thrombopoietin receptor, Mpl, in polycythemia vera (PV) platelets and megakaryocytes using an antiserum against the Mpl extracellular domain. To further examine this abnormality, w
Autor:
J L, Spivak
Publikováno v:
Seminars in oncology. 25(3 Suppl 7)
Erythropoietin (EPO) is one of the few hematopoietic growth factors that behaves like a hormone. Produced primarily in the kidneys in adults, and to a small extent in the liver, EPO acts to promote the proliferation and maintain the survival of eryth
Publikováno v:
Experimental hematology. 24(2)
The murine erythropoietin-dependent erythroleukemia cell line, HCD-57, was employed to study the cell cycle-specific behavior of erythropoietin. Cell cycle duration for HCD-57 cells was approximately 12 hours and was uninfluenced by erythropoietin. P