Výsledky vyhledávání

Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients

Autor: Willy Kueng, J L Roesel, J M Schlaeppi, M Litschgi, M Zuber, Christopher C. Benz, Heinz Mueller, Serenella Eppenberger-Castori, Manfred Schmitt, John A. Foekens, Urs Eppenberger, Alex Matter, K Luescher

Publikováno v: Journal of Clinical Oncology, 16(9), 3129-3136. American Society of Clinical Oncology

PURPOSE To compare the prognostic impact of tumor angiogenesis factors (vascular endothelial growth factor [VEGF], angiogenin, and basic fibroblast growth factor [bFGF]), tumor proteolysis factors (urokinase-type plasminogen activator [uPA] and plasm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d2602bd02879e80659bdbbf7057f37
https://doi.org/10.1200/jco.1998.16.9.3129

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pH-sensitive nanoparticles: an effective means to improve the oral delivery of HIV-1 protease inhibitors in dogs

Autor: J C, Leroux, R M, Cozens, J L, Roesel, B, Galli, E, Doelker, R, Gurny

Publikováno v: Pharmaceutical research. 13(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d767b380c14914c4f8929781d11c55c
https://pubmed.ncbi.nlm.nih.gov/8692747

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Benzopyranones and benzothiopyranones: a class of tyrosine protein kinase inhibitors with selectivity for the v-abl kinase

Autor: J F, Geissler, J L, Roesel, T, Meyer, U P, Trinks, P, Traxler, N B, Lydon

Publikováno v: Cancer research. 52(16)

Abelson murine leukemia virus is an acutely transforming replication-defective virus which encodes a transforming protein with tyrosine-specific protein kinase activity. A variety of benzopyranone and benzothiopyranone derivatives have been identifie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9e7a7df0fd11d29d1513cee1dfcdf8d
https://pubmed.ncbi.nlm.nih.gov/1643641

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Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors

Autor: J F, Geissler, P, Traxler, U, Regenass, B J, Murray, J L, Roesel, T, Meyer, E, McGlynn, A, Storni, N B, Lydon

Publikováno v: The Journal of biological chemistry. 265(36)

Various derivatives of thiazolidine-diones have been identified as tyrosine protein kinase inhibitors. The epidermal growth factor (EGF) receptor kinase and c-src kinase were inhibited in vitro with IC50 values in the range of 1-7 microM. The v-abl t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91d1c038a37017741b55ad199ef96b8c
https://pubmed.ncbi.nlm.nih.gov/2176210

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