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Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin

Autor: Pierre Sokoloff, D. Levesque, D Schott, J C Schwartz, Marie-Pascale Martres, C. Pilon, Evelyne Souil, Jorge Diaz, Bruno Giros, J L Morgat

Publikováno v: Scopus-Elsevier

We have identified 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin ([3H]7-OH-DPAT) as a selective probe for the recently cloned dopamine D3 receptor and used it to assess the presence of this receptor and establish its distribution and properties in br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06505ceceb7e1c6c9e2b6d928ea6a430
https://doi.org/10.1073/pnas.89.17.8155

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Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density

Autor: V C, Mosqueira, P, Legrand, J L, Morgat, M, Vert, E, Mysiakine, R, Gref, J P, Devissaguet, G, Barratt

Publikováno v: Pharmaceutical research. 18(10)

To study the pharmacokinetics and biodistribution of novel polyethyleneglycol (PEG) surface-modified poly(rac-lactide) (PLA) nanocapsules (NCs) and to investigate the influence of PEG chain length and content.The biodistribution and plasma clearance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cede7fd63dda952033a3e5573673226
https://pubmed.ncbi.nlm.nih.gov/11697466

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Involvement of human plasma angiotensin I-converting enzyme in the degradation of the haemoregulatory peptide N-acetyl-seryl-aspartyl-lysyl-proline

Autor: N Saez-Servent, J L Morgat, Josiane Thierry, Wolfgang Voelter, Maryse Lenfant, K.-J. Rieger, Joanna Wdzieczak-Bakala, M P Papet

The degradation of N-Ac-Ser-Asp-Lys-Pro (AcSDKP), a negative regulator controlling the proliferation of the haematopoietic stem cell, by enzymes present in human plasma, has been investigated. Radiolabelled AcSD[4-3H]KP ([3H]AcSDKP, 1 mM) was complet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9649a68a4493e688275b0397cba918
https://europepmc.org/articles/PMC1137706/

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Le marquage au tritium des hormones polypeptidiques : outils précieux en endocrinologie moléculaire

Autor: J.-L. Morgat

Publikováno v: Revue Générale Nucléaire. :309-313

Presentation des voies chimiques et enzymatiques de la tritiation d'hormones polypeptidiques

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::802d81060a9df74d32d2aede89e557d5
https://doi.org/10.1051/rgn/19894309

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[4-3H]-labelling of the calcium ionophore A 23187 (calcimycin)

Autor: D. Schott, P. Beaulieu, M. Prudhomme, J. L. Morgat, G. Jeminet

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 27:1451-1456

[4-3H-labelled]-A 23187 (or calcimycin) has been obtained as a magnesium salt from the corresponding 4-bromo derivative using tritiated hydrogen gas in the presence of 10% Pd/C catalyst. The specific radioactivity proved to be 50.6 Ci/mmole (1872.2 G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0be501c0fe14fdb8be2226a294f4539
https://doi.org/10.1002/jlcr.2580271212

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