Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J L Krahenbuhl"'
Autor:
Thomas P. Gillis, David M. Scollard, Diana L. Williams, Linda B. Adams, J. L. Krahenbuhl, Richard W. Truman
Publikováno v:
Clinical Microbiology Reviews. 19:338-381
SUMMARYLeprosy is best understood as two conjoined diseases. The first is a chronic mycobacterial infection that elicits an extraordinary range of cellular immune responses in humans. The second is a peripheral neuropathy that is initiated by the inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7dccbe67d22a450e7470a9c22d08f7
https://doi.org/10.1128/cmr.19.2.338-381.2006
https://doi.org/10.1128/cmr.19.2.338-381.2006
Down Regulation of Macrophage Activation in Brugia pahangi -Infected Jirds ( Meriones unguiculatus )
Publikováno v:
Infection and Immunity. 66:1063-1069
The macrophage is a major component of the inflammatory response induced by lymphatic tissue-dwelling filariae. Intraperitoneal (i.p.) infections with Brugia pahangi in Mongolian gerbils, or jirds ( Meriones unguiculatus ), induce a peritoneal inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f32623a99c0e30f7281e0e28ea8a5de
https://doi.org/10.1128/iai.66.3.1063-1069.1998
https://doi.org/10.1128/iai.66.3.1063-1069.1998
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2265-2269
Because of the limited chemotherapeutic approaches available to treat reactivated latent Toxoplasma gondii infection manifested as toxoplasmic encephalitis in AIDS patients, investigation of novel chemotherapeutic agents is warranted. Several poloxam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75c22e81b1ea7a625da6cc37090b98c
https://doi.org/10.1128/aac.37.11.2265
https://doi.org/10.1128/aac.37.11.2265
Publikováno v:
The Journal of Immunology. 147:2340-2345
IFN-gamma is an important mediator of cellular resistance against microbial pathogens and tumor cells due in part to its potent capacity to activate macrophages for enhanced cytotoxicity. The present study demonstrates that TNF-alpha regulates the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b19a2a7ff3259935034891d9e3fa2a
https://doi.org/10.4049/jimmunol.147.7.2340
https://doi.org/10.4049/jimmunol.147.7.2340
Publikováno v:
The Journal of Immunology. 144:2725-2729
Recent studies show the importance of a single amino acid, L-arginine, as a necessary substrate for activated macrophage-mediated cytotoxic activity for tumor target cells and microbiostatic function for Cryptococcus neoformans. The present studies w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d2b468b1c2d9b7d215d9c3610a3d67
https://doi.org/10.4049/jimmunol.144.7.2725
https://doi.org/10.4049/jimmunol.144.7.2725
Autor:
R W, Truman, J L, Krahenbuhl
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 69(1)
Mycobacterium leprae remain a rare research resource. They cannot be cultivated on artificial media, and the only established means to quantify viability of M. leprae has been by its relative growth in the foot pads of conventional mice (MFP). The MF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e35135485d46efebb514c6ece7846b9
https://pubmed.ncbi.nlm.nih.gov/11480310
https://pubmed.ncbi.nlm.nih.gov/11480310
Autor:
C M, Martelli, M M, Stefani, M K, Gomes, P F, Rebello, S, Peninni, K, Narahashi, A L, Maroclo, M B, Costa, S A, Silva, S C, Sacchetim, J A, Nery, A M, Salles, T P, Gillis, J L, Krahenbuhl, A L, Andrade
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 68(3)
In Brazil, there is little information about the clinical and epidemiological characteristics of paucibacillary, single skin lesion leprosy patients (SSL-PB). Only recently has the official notification system distinguished leprosy patients with a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e7792ea6609f778ec36f4144153cecf
https://pubmed.ncbi.nlm.nih.gov/11221086
https://pubmed.ncbi.nlm.nih.gov/11221086
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 68(1)
Mycobacterium leprae is uncultivable on artificial medium, but viability can be maintained without multiplication for a limited time in vitro. In this study, we evaluated gamma-irradiation (gamma-irr) as a means to kill this slowly growing organism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::235b644a08c489eaa65c86ac8919d694
https://pubmed.ncbi.nlm.nih.gov/10834063
https://pubmed.ncbi.nlm.nih.gov/10834063
Publikováno v:
Public health reports (Washington, D.C. : 1974). 109(6)
Because of the similarities in causative agents of Hansen's disease and tuberculosis, Hansen's disease research is now being used in the identification, treatment, and prevention of tuberculosis. Numerous studies are under way to screen and develop n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba7db751af6b73bb1ff7117911c20d27
https://pubmed.ncbi.nlm.nih.gov/7800793
https://pubmed.ncbi.nlm.nih.gov/7800793
Autor:
J L, Krahenbuhl, L B, Adams
Publikováno v:
Immunology series. 60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37d0585960671aa2a4ba2439e0e594c6
https://pubmed.ncbi.nlm.nih.gov/8251574
https://pubmed.ncbi.nlm.nih.gov/8251574