Zobrazeno 1 - 10
of 188
pro vyhledávání: '"J L Klaus"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1600-1603
We evaluated the antimalarial effects of vinyl sulfone cysteine proteinase inhibitors. A number of vinyl sulfones strongly inhibited falcipain, a Plasmodium falciparum cysteine proteinase that is a critical hemoglobinase. In studies of cultured paras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c573fc98397c36c34c2a34ab5651908
https://doi.org/10.1128/aac.40.7.1600
https://doi.org/10.1128/aac.40.7.1600
Autor:
Kaster, Sven H. M.1, Lei Zhu1, Lyon, William L.1, Rulin Ma1, Ammann, Stephen E.1, White, M. Christina1 mcwhite7@illinois.edu
Publikováno v:
Science. 9/6/2024, Vol. 385 Issue 6713, p1067-1076. 10p. 5 Diagrams.
Autor:
Bradley A. Katz, Mary E. McGrath, F. R. Mistry, C. J. Linnevers, M. G. Barnes, Randall Armstrong, Dieter Brömme, James T. Palmer, J L Klaus
Publikováno v:
Protein Science. 6:919-921
Cathepsin K is a cysteine protease of the papain family, which is predominantly expressed in osteoclasts, and is regarded as a key protease in bone remodeling. To facilitate structural studies of the protein, the wild-type sequence of the protease ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67477802b3a5d19fe09340879fc6111f
https://doi.org/10.1002/pro.5560060421
https://doi.org/10.1002/pro.5560060421
Autor:
Hintzen JCJ; University of Gothenburg, Department of Chemistry and Molecular Biology, Wallenberg Centre for Molecular and Translational Medicine, Kemigården 4, 412 96, Göteborg, Sweden., Abujubara H; University of Gothenburg, Department of Chemistry and Molecular Biology, Wallenberg Centre for Molecular and Translational Medicine, Kemigården 4, 412 96, Göteborg, Sweden., Tietze D; University of Gothenburg, Department of Chemistry and Molecular Biology, Wallenberg Centre for Molecular and Translational Medicine, Kemigården 4, 412 96, Göteborg, Sweden., Tietze AA; University of Gothenburg, Department of Chemistry and Molecular Biology, Wallenberg Centre for Molecular and Translational Medicine, Kemigården 4, 412 96, Göteborg, Sweden.
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Jul 05; Vol. 30 (38), pp. e202401103. Date of Electronic Publication: 2024 Jun 19.
Autor:
S L, Biroc, S, Gay, K, Hummel, C, Magill, J T, Palmer, D R, Spencer, S, Sa, J L, Klaus, B A, Michel, D, Rasnick, R E, Gay
Publikováno v:
Arthritis and rheumatism. 44(3)
Cysteine proteases are postulated to play a role in tissue destruction in the joints of animals with arthritis. The purpose of the present study was to confirm the concept that cysteine proteases are enzymes involved in the pathology of rheumatoid ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd5a4e15044ec4a0becfc7c20ce23dec
https://pubmed.ncbi.nlm.nih.gov/11263786
https://pubmed.ncbi.nlm.nih.gov/11263786
Autor:
K I, Hulkower, C C, Butler, B E, Linebaugh, J L, Klaus, D, Keppler, V L, Giranda, B F, Sloane
Publikováno v:
European journal of biochemistry. 267(13)
Cathepsin B and in particular cell-surface and secreted cathepsin B has been implicated in the invasive and metastatic phenotype of numerous types of cancer. We describe here a method to easily survey cancer cell lines for cathepsin B activity using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8877091bc44dc217b4f7dc25e1839e2
https://pubmed.ncbi.nlm.nih.gov/10866820
https://pubmed.ncbi.nlm.nih.gov/10866820
Autor:
C J, Linnevers, M E, McGrath, R, Armstrong, F R, Mistry, M G, Barnes, J L, Klaus, J T, Palmer, B A, Katz, D, Brömme
Publikováno v:
Protein science : a publication of the Protein Society. 6(4)
Cathepsin K is a cysteine protease of the papain family, which is predominantly expressed in osteoclasts, and is regarded as a key protease in bone remodeling. To facilitate structural studies of the protein, the wild-type sequence of the protease ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2792cda47576049504b42f02db834f5f
https://pubmed.ncbi.nlm.nih.gov/9098904
https://pubmed.ncbi.nlm.nih.gov/9098904
Peptidyl vinyl sulphones are a novel class of extremely potent and specific cysteine protease inhibitors. They are highly active against the therapeutically important cathepsins O2, S and L. The highest kinact/Ki values exceed 107 M-1·s-1 for cathep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8320fa9acb1ce914d34fa5e791ae114b
https://europepmc.org/articles/PMC1217200/
https://europepmc.org/articles/PMC1217200/
Sleep Problems in Adults With ADHD: Prevalences and Their Relationship With Psychiatric Comorbidity.
Publikováno v:
Journal of Attention Disorders; Nov2024, Vol. 28 Issue 13, p1642-1652, 11p
Autor:
Lemke, Carina1 (AUTHOR), Jílková, Adéla2 (AUTHOR), Ferber, Dominic1 (AUTHOR), Braune, Annett3 (AUTHOR), On, Anja1 (AUTHOR), Johe, Patrick4 (AUTHOR), Zíková, Alena5 (AUTHOR), Schirmeister, Tanja4 (AUTHOR), Mareš, Michael2 (AUTHOR), Horn, Martin2 (AUTHOR) martin.horn@uochb.cas.cz, Gütschow, Michael1 (AUTHOR) guetschow@uni-bonn.de
Publikováno v:
Chemistry - A European Journal. 11/7/2022, Vol. 28 Issue 62, p1-11. 11p.