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pro vyhledávání: '"J L Derham"'
Autor:
C Qi, Dionisios Stavroulias, J L Derham, Michael Skwarski, E Belcher, Joshua A. Bull, P Ferencz, Chu K-Y., Fergus V. Gleeson, Daniel P. Bulte, Paula L. Croal, Francesca M. Buffa, Adrian L. Harris, O’Connor Jpb., Marcus Green, Harris Bhl., H Flight, Leticia Campo, D O’Reilly, J Chauhan, Jane Holmes, Mark McCole, Geoff S. Higgins, Gonzalo Rodriguez-Berriguete, F Di Chiara, W G McKenna, Eugene Teoh, Lisa K. Folkes, Ruth MacPherson, Daniel R. McGowan, Philip S. Macklin, Remko Prevo
Publikováno v:
Clin Cancer Res
Purpose: Tumor hypoxia fuels an aggressive tumor phenotype and confers resistance to anticancer treatments. We conducted a clinical trial to determine whether the antimalarial drug atovaquone, a known mitochondrial inhibitor, reduces hypoxia in non