Výsledky vyhledávání

Improvement on binding of chondroitin sulfate derivatives to midkine by increasing hydrophobicity

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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idUS. Depósito de Investigación de la Universidad de Sevilla

The interactions between chondroitin sulfate (CS) and a wide number of proteins modulate important biological processes. Here, the binding properties to midkine and pleiotrophin of sulfated, fully protected intermediates, typically obtained in the ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fc317a928943f5190f4c8e646b3871
http://hdl.handle.net/10261/148554

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Characterization of Annexin A1 Glycan Binding Reveals Binding to Highly Sulfated Glycans with Preference for Highly Sulfated Heparan Sulfate and Heparin

Autor: Michiko N. Fukuda, Peter H. Seeberger, P. Bindschädler, Christian Noti, Tim Horlacher, Marie-Lyn Hecht, J. L. de Paz, David F. Smith

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Annexin A1 is a multifunctional, calcium-dependent phospholipid binding protein involved in a host of processes including inflammation, regulation of neuroendocrine signaling, apoptosis, and membrane trafficking. Binding of annexin A1 to glycans has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d942e64c25ff3580c0515280c5de2d65
https://doi.org/10.1021/bi101121a

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Akademický článek

Chondroitin Sulfate-Coated Heteroduplex-Molecular Spherical Nucleic Acids.

Autor: Laine T; Department of Chemistry, University of Turku, 20500, Turku, Finland., Deshpande P; Turku Bioscience Centre, University of Turku, Åbo Akademi University, 20520, Turku, Finland., Tähtinen V; Department of Chemistry, University of Turku, 20500, Turku, Finland., Coffey ET; Turku Bioscience Centre, University of Turku, Åbo Akademi University, 20520, Turku, Finland., Virta P; Department of Chemistry, University of Turku, 20500, Turku, Finland.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Nov 15, pp. e202400908. Date of Electronic Publication: 2024 Nov 15.

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The activation of fibroblast growth factors by heparin: synthesis, structure, and biological activity of heparin-like oligosaccharides

Autor: J L, de Paz, J, Angulo, J M, Lassaletta, P M, Nieto, M, Redondo-Horcajo, R M, Lozano, G, Giménez-Gallego, M, Martín-Lomas

Publikováno v: Chembiochem : a European journal of chemical biology. 2(9)

An effective strategy has been designed for the synthesis of oligosaccharides of different sizes structurally related to the regular region of heparin; this is illustrated by the preparation of hexasaccharide 1 and octasaccharide 2. This synthetic st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a985e671fcfa9ab7aa1b35df513016c4
https://pubmed.ncbi.nlm.nih.gov/11828504

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Akademický článek

Sweet but Challenging: Tackling the Complexity of GAGs with Engineered Tailor-Made Biomaterials.

Autor: Le Pennec J; U1292 Biosanté, INSERM, CEA, Univ. Grenoble Alpes, CNRS EMR 5000 Biomimetism and Regenerative Medicine, Grenoble, F-38054, France., Picart C; U1292 Biosanté, INSERM, CEA, Univ. Grenoble Alpes, CNRS EMR 5000 Biomimetism and Regenerative Medicine, Grenoble, F-38054, France., Vivès RR; Univ. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France., Migliorini E; U1292 Biosanté, INSERM, CEA, Univ. Grenoble Alpes, CNRS EMR 5000 Biomimetism and Regenerative Medicine, Grenoble, F-38054, France.

Publikováno v: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Mar; Vol. 36 (11), pp. e2312154. Date of Electronic Publication: 2023 Dec 14.

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Akademický článek

High-Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC-SIGN and Langerin.

Autor: Herrera-González I; Department of Organic Chemistry, Faculty of Chemistry, University of Seville, C/ Profesor García González 1, 41012, Sevilla, Spain.; Present address: DCM, UMR 5250, Université Grenoble Alpes, CNRS, 570 Rue de la Chimie, 38000, Grenoble, France., González-Cuesta M; Department of Organic Chemistry, Faculty of Chemistry, University of Seville, C/ Profesor García González 1, 41012, Sevilla, Spain., Thépaut M; Institut de Biologie Structurale, Université Grenoble Alpes, CNRS, CEA, 38000, Grenoble, France., Laigre E; Institut de Biologie Structurale, Université Grenoble Alpes, CNRS, CEA, 38000, Grenoble, France.; DCM, UMR 5250, Université Grenoble Alpes, CNRS, 570 Rue de la Chimie, 38000, Grenoble, France., Goyard D; DCM, UMR 5250, Université Grenoble Alpes, CNRS, 570 Rue de la Chimie, 38000, Grenoble, France., Rojo J; Instituto de Investigaciones Químicas (IIQ), CSIC - Universidad de Sevilla, Américo Vespucio 49, 41092, Sevilla, Spain., García Fernández JM; Instituto de Investigaciones Químicas (IIQ), CSIC - Universidad de Sevilla, Américo Vespucio 49, 41092, Sevilla, Spain., Fieschi F; Institut de Biologie Structurale, Université Grenoble Alpes, CNRS, CEA, 38000, Grenoble, France.; Institut Universitaire de France (IUF), Paris, France., Renaudet O; DCM, UMR 5250, Université Grenoble Alpes, CNRS, 570 Rue de la Chimie, 38000, Grenoble, France., Nieto PM; Instituto de Investigaciones Químicas (IIQ), CSIC - Universidad de Sevilla, Américo Vespucio 49, 41092, Sevilla, Spain., Ortiz Mellet C; Department of Organic Chemistry, Faculty of Chemistry, University of Seville, C/ Profesor García González 1, 41012, Sevilla, Spain.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Jan 08; Vol. 30 (2), pp. e202303041. Date of Electronic Publication: 2023 Nov 14.

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