Zobrazeno 1 - 10
of 58
pro vyhledávání: '"J L, Witztum"'
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 9, Pp 1996-2004 (1995)
Oxidative modification of LDL plays an important role in early atherogenesis but the mechanisms, nonenzymatic and/or enzymatic, by which LDL is oxidized in vivo remain to be established. Several lines of evidence suggest that cellular 15-lipoxygenase
Externí odkaz:
https://doaj.org/article/a5ce644f0ddf4e84bb5a37feff3a35da
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 6, Pp 956-965 (1994)
Previous studies have shown that treatment of guinea pigs with lovastatin alters the composition and the metabolic properties of circulating low density lipoprotein (LDL). Specifically, LDL isolated from lovastatin-treated animals is cleared from pla
Externí odkaz:
https://doaj.org/article/91eda47e31d94e64a44a6f606dfb70f0
Autor:
E. Bruckert, R. Geary, S.G. Hughes, S. Tsmikas, J. L. Witztum, A. Digenio, Daniel Gaudet, Erik S.G. Stroes, A. Hsieh, K. R. Williams, V. Alexander, Ioanna Gouni-Berthold, Andres Gelrud
Publikováno v:
Pancreatology. 18:S101
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cba201d09839faeb657b0829a8421de7
https://doi.org/10.1016/j.pan.2018.05.273
https://doi.org/10.1016/j.pan.2018.05.273
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 1, Pp 92-103 (1985)
In previous animal studies, bile acid sequestrant resins have been shown to increase the fractional catabolic rate (FCR) of a low density lipoprotein (LDL) tracer isolated from a normal donor animal and to increase hepatic LDL-receptor activity. In a
Externí odkaz:
https://doaj.org/article/ed2087f9c2d64143b18abe28576cd777
Publikováno v:
Journal of Lipid Research, Vol 25, Iss 10, Pp 1109-1116 (1984)
We previously showed that immunization of guinea pigs with reductively glucosylated guinea pig low density lipoprotein (LDL) or albumin resulted in the formation of antibodies specific for the glucosylated protein. The present studies were done to de
Externí odkaz:
https://doaj.org/article/0a504c9b99ee4acfb198378e39aacd06
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 10, Pp 1591-1600 (1989)
Lovastatin therapy is known to induce hepatic low density lipoprotein (LDL) receptor mRNA and LDL receptor activity. Yet, in studies in humans and animals it has been difficult to demonstrate an enhancement of the plasma fractional catabolic rate (FC
Externí odkaz:
https://doaj.org/article/45079058604e48398595a96823e9cc2f
Publikováno v:
Journal of Lipid Research, Vol 30, Iss 2, Pp 225-238 (1989)
We investigated the effect of the bile acid sequestrant, colestipol hydrochloride, on the composition and metabolism of human low density lipoprotein (LDL). Colestipol treatment produced a disproportionate decrease in LDL cholesterol compared to LDL
Externí odkaz:
https://doaj.org/article/45480750e8a6475ebadb358d6d47a1f0
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 12, Pp 1466-1477 (1987)
Incubation of low density lipoprotein (LDL) with endothelial cells converts it to a form that is avidly degraded by macrophages via the acetyl LDL receptor. This modification has previously been shown to be accompanied by extensive breakdown of the m
Externí odkaz:
https://doaj.org/article/1ec53a182d124958be03b67b246152fe
Publikováno v:
Journal of Lipid Research, Vol 28, Iss 9, Pp 1098-1109 (1987)
Immunological mechanisms have been implicated in the atherogenic process since immunoglobulins are frequently found in the atherosclerotic aorta. We have previously shown that modifications of homologous low density lipoproteins (LDL) make it immunog
Externí odkaz:
https://doaj.org/article/ea8f865b75344e14951cb4a960449b91
Autor:
G A, FitzGerald, J L, Witztum
Publikováno v:
Trends in cardiovascular medicine. 11(3-4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81739613b766317031db90fb8810df50
https://pubmed.ncbi.nlm.nih.gov/11686008
https://pubmed.ncbi.nlm.nih.gov/11686008