Zobrazeno 1 - 2
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pro vyhledávání: '"J L, Wagenaars"'
Autor:
J, Dulos, F P G, Wijnands, J A J, van den Hurk-van Alebeek, M J H, van Vugt, J A C, Rullmann, J-J G, Schot, M W G D M, de Groot, J L, Wagenaars, R, van Ravestein-van Os, R L, Smets, P M, Vink, C L, Hofstra, R L H, Nelissen, H, van Eenennaam
Publikováno v:
Clinical and experimental rheumatology. 31(4)
For many years the p38 MAP kinase (MAPK) has been a major anti-inflammatory target for the development of an oral therapy for rheumatoid arthritis (RA). However, disappointing results from Phase II clinical studies suggest that adaptations may occur,
Publikováno v:
Journal of Steroid Biochemistry, 21(2), 173. Elsevier
Journal of Steroid Biochemistry, 21(2), 173-8
Journal of Steroid Biochemistry, 21(2), 173-8
In cytosol of the hippocampus corticosterone displays highest affinity for the sites that remain available for binding in the presence of excess RU 26988, which is shown to be a "pure" glucocorticoid. A rather high affinity (greater than or equal to