Zobrazeno 1 - 6 of 6 pro vyhledávání: '"J L, Rutter"'
1
A twofold increase in BRCA mutation related prostate cancer among Ashkenazi Israelis is not associated with distinctive histopathology
Autor: Stephen M. Hewitt, R D Ronchetti, J. Fisher-Fischbein, Paul H. Duray, B Maslansky, Gad Rennert, Stephen B. Gruber, Alf Fischbein, Jose Iscovich, R M Giusti, J L Rutter, Jeffery P. Struewing, M Konichezky, Mark H. Greene, Laurence S. Freedman
Publikováno v: Scopus-Elsevier
The magnitude of the risk of prostate cancer among Ashkenazi Jewish carriers of the common mutations in the BRCA1 and BRCA2 genes, the so-called Ashkenazi BRCA founder mutations ( BRCA1 185delAG and 5382insC, and BRCA2 6174delT), remains uncertain. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4460214212a41f97971c4a1943e2763
https://europepmc.org/articles/PMC1735297/
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2
Interstitial collagenases as markers of tumor progression
Autor: C E, Brinckerhoff, J L, Rutter, U, Benbow
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(12)
Degradation of the extracellular matrix is the sine qua non of tumor invasion and metastasis. Most of this degradation is mediated by matrix metalloproteinases (MMPs), a family of enzymes that, collectively, degrades the extracellular matrix. Althoug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8d6373977a4a33c01f35f1ebd6f9ef6
https://pubmed.ncbi.nlm.nih.gov/11156241
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3
A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter creates an Ets binding site and augments transcription
Autor: J L, Rutter, T I, Mitchell, G, Butticè, J, Meyers, J F, Gusella, L J, Ozelius, C E, Brinckerhoff
Publikováno v: Cancer research. 58(23)
Matrix metalloproteinases (MMPs) facilitate cellular invasion by degrading the extracellular matrix, and their regulation is partially dependent on transcription. Binding sites for members of the Ets family of transcription factors are present within
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::35f5f22591c4c9d6ce618c3d6376cc07
https://pubmed.ncbi.nlm.nih.gov/9850057
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4
Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas
Autor: L, Xu, D, Sgroi, C J, Sterner, R L, Beauchamp, D M, Pinney, S, Keel, K, Ueki, J L, Rutter, A J, Buckler, D N, Louis
Publikováno v: Cancer research. 54(20)
The CDKN2 gene that encodes the cell cycle regulatory protein cyclin-dependent kinase-4 inhibitor (p16) has recently been mapped to chromosome 9p21. Frequent homozygous deletions of this gene have been documented in cell lines derived from different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dcd99fb5d7aa9923b091413718d999d
https://pubmed.ncbi.nlm.nih.gov/7923151
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5
The synthesis of 1,4,5-trialkyl-2-pyrazolines from monoalkylhydrazines and aliphatic aldehydes
Autor: H. R. Havens, J. L. Rutter, Norman Rabjohn
Publikováno v: Journal of Heterocyclic Chemistry. 3:413-417
It has been found that the thermal decomposition of heptanal methylhydrazone affords 5-hexyl-1-methyl-4-pentyl-2-pyrazoline (I), in addition to heptanenitrile and methylamine. The formation of I suggests the synthesis of 1,4, 5-trialkyl-2-pyrazolines
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9a012c1b5a210698f0709716a1cc338
https://doi.org/10.1002/jhet.5570030404
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