Výsledky vyhledávání - "J L, RADOMSKI"

Nitrosamine Formation in Bladder Infections and its Role in the Etiology of Bladder Cancer

Autor: J L, Radomski, D, Greenwald, W L, Hearn, N L, Block, F M, Woods

Publikováno v: Journal of Urology. 120:48-50

Dimethylnitrosamine, a powerful carcinogen, is produced in the urine of patients with urinary tract infections of Proteus mirabilis and Escherichia coli when nitrite is present. Treatment with tetracycline antibiotics does not enhance the concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7d9251cea4856d02eea38a3e614956
https://doi.org/10.1016/s0022-5347(17)57035-4

Zobrazit plný text záznamu

Isolation of the glucuronic acid conjugate of n-hydroxy-4-aminobiphenyl from dog urine and its mutagenic activity

Autor: J L, Radomski, W L, Hearn, T, Radomski, H, Moreno, W E, Scott

Publikováno v: Cancer research. 37(6)

The glucuronic acid conjugate of N-hydroxy-4-aminobiphenyl (NOH-4-ABP) has been isolated in relatively pure form from the urine of dogs given 4-aminobiphenyl, utilizing molecular size, ion exchange, adsorption, and partition chromatography. This conj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9231a7cc3da9b0080fae9fc13d18bf5
https://pubmed.ncbi.nlm.nih.gov/322861

Zobrazit plný text záznamu

Failure of the N-oxodized metabolites of some carcinogenic amines to induce tumors in normal and wounded rat skin

Autor: E, Brill, J L, Radomski, W E, MacDonald

Publikováno v: Research communications in chemical pathology and pharmacology. 18(2)

The skin of Osborne-Mendel and Sprague-Dawley rats was treated by repeated topical application of 1- and 2-naphthylamine, 4-biphenylamine and their corresponding N-arylhydroxylamine and nitroso derivatives for 52 weeks. In addition, the possibility o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af1e38640449b72348634e8cef2fcca2
https://pubmed.ncbi.nlm.nih.gov/918350

Zobrazit plný text záznamu

Failure of ascrobic acid to inhibit the metabolic N-oxidation of the bladder carcingen 4-biphenylamine

Autor: E, Brill, J L, Radomski

Publikováno v: Research communications in chemical pathology and pharmacology. 16(1)

The effect of L-ascorbic acid on the in vivo metabolic N-oxidation of the bladder carcinogen 4-biphenylamine has been investigated in the dog. Gas chromatographic analysis of the urines of dogs receiving concomitant oral doses of L-ascorbic acid and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4cd909ef93a31b1ee865c190b2c29aae
https://pubmed.ncbi.nlm.nih.gov/841184

Zobrazit plný text záznamu

Cocarcinogenic interaction between D,L-tryptophan and 4-aminobiphenyl or 2-naphthylamine in dogs

Autor: J L, Radomski, T, Radomski, W E, MacDonald

Publikováno v: Journal of the National Cancer Institute. 58(6)

Administration of a dietary supplement of 6 g D,L tryptophan/day for 4 1/2 years following the administration of a single dose of 50 mg 4-aminobiphenyl/kg produced a bladder tumor in 1 of 4 beagle dogs. No tumors were observed in 6 dogs given the sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::486acef9f364687a9d17bb8141b669e3
https://pubmed.ncbi.nlm.nih.gov/864760

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání