Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J L, Nichol"'
Autor:
H Hiesberger, Georg Schett, W Füreder, J L Nichol, U Firbas, Josef S. Smolen, Stefan Winkler, Wolfgang R. Sperr, J Pistillo
Publikováno v:
Lupus. 11:221-226
Thrombocytopenia is a common phenomenon in patients suffering from systemic lupus erythematosus (SLE). The cause of thrombocytopenia in SLE, however, is poorly understood. In this study, 100 patients with SLE were evaluated for serum thrombopoietin l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b817d679e262743ce89df4848b6214
https://doi.org/10.1191/0961203302lu177oa
https://doi.org/10.1191/0961203302lu177oa
Autor:
J L Nichol, R Ramon, I Cordiano, Raffaella Scandellari, Antonio Girolami, Fabrizio Fabris, Agostino Steffan
Publikováno v:
European Journal of Haematology. 64:151-156
Chronic isolated hereditary macrothrombocytopenia (CHMT) is a congenital form of macrothrombocytopenia that seems to be due to defective production secondary to a disturbance in megakaryocyte fragmentation. To better understand the pathogenesis of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8e35edb12a1b5a26bbcc4347d179bd3
https://doi.org/10.1034/j.1600-0609.2000.90072.x
https://doi.org/10.1034/j.1600-0609.2000.90072.x
Publikováno v:
European journal of haematology. 64(3)
Chronic isolated hereditary macrothrombocytopenia (CHMT) is a congenital form of macrothrombocytopenia that seems to be due to defective production secondary to a disturbance in megakaryocyte fragmentation. To better understand the pathogenesis of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::556cf59dd14a18fe742955bdbf0afd7f
https://pubmed.ncbi.nlm.nih.gov/11860451
https://pubmed.ncbi.nlm.nih.gov/11860451
Autor:
N, Faraday, J J, Rade, D C, Johns, G, Khetawat, S J, Noga, J F, DiPersio, Y, Jin, J L, Nichol, J S, Haug, P F, Bray
Publikováno v:
Blood. 94(12)
Investigation of the molecular basis of megakaryocyte (MK) and platelet biology has been limited by an inadequate source of genetically manipulable cells exhibiting physiologic MK and platelet functions. We hypothesized that ex vivo cultured MKs woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49225a653d9bfb6b486c7f9024cc91f5
https://pubmed.ncbi.nlm.nih.gov/10590053
https://pubmed.ncbi.nlm.nih.gov/10590053
Autor:
J L, Cole, U M, Marzec, C J, Gunthel, S, Karpatkin, L, Worford, I B, Sundell, J L, Lennox, J L, Nichol, L A, Harker
Publikováno v:
Blood. 91(9)
Thrombocytopenia has been characterized in six patients infected with human immunodeficiency virus (HIV) with respect to the delivery of viable platelets into the peripheral circulation (peripheral platelet mass turnover), marrow megakaryocyte mass (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f555fd2ab052f22d750ed42d5746ca43
https://pubmed.ncbi.nlm.nih.gov/9558379
https://pubmed.ncbi.nlm.nih.gov/9558379
Autor:
H, Schrezenmeier, M, Griesshammer, A, Hornkohl, J L, Nichol, T, Hecht, H, Heimpel, B, Kubanek, A, Raghavachar
Publikováno v:
British journal of haematology. 100(3)
In an attempt to evaluate the role of thrombopoietin (TPO) in the pathobiology of aplastic anaemia (AA), we have examined TPO levels in sera from 54 AA patients and 119 healthy controls. A total of 92 samples were collected from AA patients: 43 sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11d85b7e3f291c9087d49eb9f5498351
https://pubmed.ncbi.nlm.nih.gov/9504643
https://pubmed.ncbi.nlm.nih.gov/9504643
Publikováno v:
Blood. 90(9)
The MpL ligand (ML) is a potent stimulus for thrombocytopoiesis. To create an in vivo model of ML deficiency, we injected dogs with a recombinant human ML (rhML) to determine whether cross-reacting antibodies would develop and cause thrombocytopenia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3b0fd226c1049cbf9c4cf82d6ddf909
https://pubmed.ncbi.nlm.nih.gov/9345029
https://pubmed.ncbi.nlm.nih.gov/9345029
Autor:
L A, Harker, U M, Marzec, A B, Kelly, E, Cheung, A, Tomer, J L, Nichol, S R, Hanson, R B, Stead
Publikováno v:
Blood. 89(1)
This report examines the effects on hematopoietic regeneration of pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) (2.5 micrograms/ kg/d) alone and in combination with recombinant human granulocyte colony stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b83adcf86b484dcdf0fdfa19ef4a32c
https://pubmed.ncbi.nlm.nih.gov/8978288
https://pubmed.ncbi.nlm.nih.gov/8978288
Autor:
M M, Hokom, D, Lacey, O B, Kinstler, E, Choi, S, Kaufman, J, Faust, C, Rowan, E, Dwyer, J L, Nichol, T, Grasel, J, Wilson, R, Steinbrink, R, Hecht, D, Winters, T, Boone, P, Hunt
Publikováno v:
Blood. 86(12)
Megakaryocyte growth and development factor (MGDF) is a potent inducer of megakaryopoiesis in vitro and thrombopoiesis in vivo. The effects of MGDF appear to be lineage-selective, making this cytokine an ideal candidate for use in alleviating clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::524c65bb567dffe371aa790556ab777e
https://pubmed.ncbi.nlm.nih.gov/8541537
https://pubmed.ncbi.nlm.nih.gov/8541537
Autor:
P, Hunt, Y S, Li, J L, Nichol, M M, Hokom, J M, Bogenberger, S E, Swift, J D, Skrine, A C, Hornkohl, H, Lu, C, Clogston
Publikováno v:
Blood. 86(2)
The isolation and cloning of the ligand for the cytokine receptor, Mpl, have been recently described. In this report we present details of the purification of this novel cytokine (megakaryocyte growth and development factor [MGDF]) from aplastic cani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57d39574396e6beb7a61f411a414b809
https://pubmed.ncbi.nlm.nih.gov/7541666
https://pubmed.ncbi.nlm.nih.gov/7541666