Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J L, Liesveld"'
TGF-beta down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors
Publikováno v:
The Journal of Immunology. 159:117-125
Development of lymphoid progenitors in vivo requires interaction with a bone marrow stromal microenvironment containing multiple cytokines involved in the development of nonlymphoid hemopoietic lineages. We tested the effect of one such cytokine, TGF
Publikováno v:
The Journal of Immunology. 152:5250-5258
An in vitro culture system in which bone marrow-derived fibroblast-like cells support the growth of TdT+ colonies derived from CD34+/CD10- human bone marrow progenitor cells has recently been described. The regulatory role of cytokines during early B
Autor:
J M, Bennett, M S, Young, J L, Liesveld, E, Paietta, K B, Miller, H M, Lazarus, R D, Marsh, W R, Friedenberg, H T, Saba, F A, Hayes, G W, Dewald, W, Hiddemann, J M, Rowe
Publikováno v:
American journal of hematology. 66(1)
A Phase II study of GM-CSF with intermediate-dose cytarabine and mitoxantrone was conducted in patients with high-risk myelodysplastic syndrome. It was designed to evaluate if priming with growth factor could increase the efficiency of chemotherapy.
Autor:
J M, Rowe, J L, Liesveld
Publikováno v:
Cancer treatment and research. 99
Over the past decade, with the advent of hematopoietic growth factors, major strides have been made and multiple studies have attempted to define the use of these cytokines in acute leukemia. It is perhaps disappointing that, after so many studies, s
Publikováno v:
Blood. 89(3)
Relatively little is known about the relationship of lymphoid-associated gene expression to the proliferation and differentiation potential of early human bone marrow lymphoid progenitors. Surface expression of interleukin-7 (IL-7) receptor-alpha (IL
Autor:
J M, Rowe, J L, Liesveld
Publikováno v:
Bailliere's clinical haematology. 9(1)
Current induction chemotherapy regimens afford a complete remission in 60 to 80% of patients less than 60 years of age who are diagnosed with acute myelogenous leukaemia. Patients who undergo consolidation with high dose Ara-C or with autologous or a
Publikováno v:
Experimental hematology. 23(3)
Hematopoiesis is influenced by the presence of the hematopoietic microenvironment, and Dexter-type liquid culture systems represent an in vitro representation of some aspects of the microenvironment that are optimal for the propagation of myeloid pro
Publikováno v:
Leukemia. 8(12)
The capacity of normal CD34+ marrow cells and CD34+ leukemic cell lines to adhere to human umbilical vein endothelial cells has been examined. Such interactions have importance since the processes of homing and egress within the marrow microenvironme
Publikováno v:
Bone marrow transplantation. 14(2)
The isolation and characterization of primitive hematopoietic cells and their purification in sufficient numbers is important in clinical and research marrow transplantation settings. As systems for large-scale isolation and amplification of such cel
Publikováno v:
Experimental hematology. 21(10)
The pleiotropic nature of malignant fibrous histiocytomas (MFH) is manifested as mixed cellular infiltrates consisting of myofibroblasts, histiomonocytes, and neutrophils. We detail in this report the phenotypic characteristics of the human fibrous h