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Akademický článek

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Attenuation of gastrininduced gastric acid secretion by antisense oligonucleotide to the CCKB/ gastrin receptor

Autor: Y. Lopez, Josephine Lai, J. L. Junien, P. J. M. Riviere, Frank Porreca, R.K. Rao

Publikováno v: NeuroReport. 6:2373-2377

The effects of treatment with CCK receptor antagonists or administration of an antisense oligonucleotide to the gastrin receptor, on gastrin-I and cholecystokinin-8-induced acid secretion in mouse stomach were evaluated. Administration of gastrin-I (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e05b9c5ed063d1e8d30db9da5fc5e4
https://doi.org/10.1097/00001756-199511270-00023

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Autoradiographic distribution of cholinergic muscarinic receptors and serotonin2 receptors in olfactory bulbectomized (OB) rats after chronic treatment with mianserin and desipramine

Autor: M. Glennon, Brian E. Leonard, Bernadette Earley, J-L. Junien, M. Lally

Publikováno v: Human Psychopharmacology: Clinical and Experimental. 9:397-407

Bilateral removal of the olfactory bulbs in rats produces a behavioural abnormality that is defined by hyperactivity in the open-field test. This abnormality may be related to depression since these behavioural effects can be attenuated by antidepres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1ade2d91a8a5a736a7dd09cd1c7fcd2
https://doi.org/10.1002/hup.470090603

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Interaction between Neuropeptide Y and Sigma Ligands in the Modulation of CRF and Stress-Induced Alteration of Gastrointestinal Function

Autor: M. Gué, J. L. Junien

Publikováno v: Annals of the New York Academy of Sciences. 697:244-253

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fae19bec6f612cc573ebc3cefceb68
https://doi.org/10.1111/j.1749-6632.1993.tb49937.x

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Akademický článek

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In vitro stimulation of the prepubertal rat gonadotropin-releasing hormone pulse generator by leptin and neuropeptide Y through distinct mechanisms

Autor: M C, Lebrethon, E, Vandersmissen, A, Gérard, A S, Parent, J L, Junien, J P, Bourguignon

Publikováno v: Endocrinology. 141(4)

Leptin may act as a negative feedback signal to the brain in the control of appetite through suppression of neuropeptide Y (NPY) secretion and stimulation of cocaine- and amphetamine-regulated transcript (CART), a new anorectic peptide. We aimed at s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d9f141700c1d4ab9f69d120378ba289
https://pubmed.ncbi.nlm.nih.gov/10746651

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Nitric oxide modulates neuropeptide Y regulation of ion transport in mouse ileum

Autor: R K, Rao, Y, Lopez, P J, Riviere, X, Pascaud, J L, Junien, F, Porreca

Publikováno v: The Journal of pharmacology and experimental therapeutics. 278(1)

The possible involvement of nitric oxide in the regulation of intestinal ion transport induced by neuropeptide Y (NPY) was investigated by evaluating the effects of NG-methyl-L-arginine (L-NMA), L-arginine and S-nitroso-N-acetylpenicillamine (SNAP) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5cee6d1cd964a49b4f3dabe3e572715
https://pubmed.ncbi.nlm.nih.gov/8764351

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Autoradiographic evidence for the modulation of in vivo sigma receptor labeling by neuropeptide Y and calcitonin gene-related peptide in the mouse brain

Autor: P, Bouchard, F, Roman, J L, Junien, R, Quirion

Publikováno v: The Journal of pharmacology and experimental therapeutics. 276(1)

Peptides of the neuropeptide Y (NPY) and calcitonin gene-related peptide (CGRP) families have been reported to modulate, in vivo, sigma receptor systems in the mouse and rat hippocampal formation. In an attempt to determine if these interactions were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cee7f03992349810d45e1f041289e61f
https://pubmed.ncbi.nlm.nih.gov/8558435

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Review article: the hypersensitive gut--peripheral kappa agonists as a new pharmacological approach

Autor: J. L. Junien, P. Riviere

Publikováno v: Alimentary pharmacologytherapeutics. 9(2)

SUMMARY Hypersensitivity to pain is a common component of functional bowel disorders. Hyperalgesia may be induced by various stimuli which produce a cocktail of inflammatory mediators that decrease the pain threshold. Drugs able to block these periph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a435b9c0c1350cbb13038df1894c1a60
https://pubmed.ncbi.nlm.nih.gov/7605851

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Peripheral kappa-opioid receptors mediate the antinociceptive effect of fedotozine (correction of fetodozine) on the duodenal pain reflex inrat

Autor: L, Diop, P J, Rivière, X, Pascaud, J L, Junien

Publikováno v: European journal of pharmacology. 271(1)

Fedotozine has been shown to act on gastrointestinal sensitivity through peripheral kappa-opioid receptors. The present study investigated the action of fedotozine and reference compounds, morphine and (+/-)-U-50,488H, on duodenal pain in anesthetize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3b66ba43f635f6c19ca1af8753c0741f
https://pubmed.ncbi.nlm.nih.gov/7698213

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